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Mashup Score: 0
Original Article from The New England Journal of Medicine — Lutetium-177–PSMA-617 for Metastatic Castration-Resistant Prostate Cancer
Source: New England Journal of MedicineCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 4The Effect of Concomitant Proton Pump Inhibitor and Cabozantinib on the Outcomes of Patients with Metastatic Renal Cell Carcinoma - 3 year(s) ago
The Oncologist is committed to helping physicians excel in the constantly changing fields of oncology and hematology through the publication of timely reviews, original studies, and commentaries on important developments.
Source: The OncologistCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 3Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immune checkpoint inhibitor-related adverse events - 3 year(s) ago
Immune checkpoint inhibitors (ICIs) are the standard of care for the treatment of several cancers. While these immunotherapies have improved patient outcomes in many clinical settings, they bring accompanying risks of toxicity, specifically immune-related adverse events (irAEs). There is a need for clear, effective guidelines for the management of irAEs during ICI treatment, motivating the…
Categories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 0Clinicopathologic Features, Treatment Response, and Outcomes of Immune Checkpoint Inhibitor–Related Esophagitis - 3 year(s) ago
Background: Although immune checkpoint inhibitors (ICIs) have provided practice-changing outcomes in treating many cancers, ICI-related gastrointestinal toxicity can limit their use. Upper gastrointestinal toxicity is not common nor as well described as lower gastrointestinal toxicity. We aimed to characterize the clinical presentation, endoscopic and…
Source: JNCCNCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 3
Cancer immunotherapies can successfully activate immune responses towards certain tumors. However, this can also result in the development of treatment-induced immune-related adverse events (irAEs) in multiple tissues. Growing evidence suggests that cytokine production in response to these therapeutics potentiates the development of irAEs and may have predictive value as biomarkers for irAE…
Source: Trends in ImmunologyCategories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 0
Cardiovascular disease (CVD) is a major source of financial burden and distress, which has three main domains: (1) psychological distress; (2) cost-re…
Source: www.sciencedirect.comCategories: Cardiologists, Latest HeadlinesTweet-
New: Dr Slavin @sdslavin and colleagues from @MethodistHosp address #financial burden, distress and #toxicity in #cardiovascular diseases and provide action items to overcome related clinical inertia. @haiderwarraich @rohan_khera @jvaleromd @HJRyooAli https://t.co/7vWZ6fZ0BY @NIH https://t.co/YvAszelmZ0
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Mashup Score: 0Bone & Joint Research - 3 year(s) ago
Tranexamic acid toxicity in human periarticular tissues
Source: Bone & Joint PublishingCategories: Latest Headlines, RheumatologyTweet-
Tranexamic acid (TXA) is an anti-fibrinolytic medication commonly used to reduce perioperative bleeding. This study demonstrates that TXA caused significant periarticular tissue #toxicity ex vivo & in vitro at commonly used clinical concentrations https://t.co/NmcNpfL14p #ortho https://t.co/XhV0fD0TxN
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Mashup Score: 10Current issue: Trends in Immunology - 3 year(s) ago
When Eating Becomes a Pain in the GutIrritable bowel syndrome often appears following gastrointestinal infection and is marked by diarrhea, dysbiosis, fever, and intestinal pain following eating. A recent study by Aguilera-Lizarraga et al. now demonstrates that a breakdown in intestinal immunotolerance sparks an inflammatory response to typically tolerated food antigens and causes visceral…
Source: www.cell.comCategories: Allergy-Immunology, Latest HeadlinesTweet-
Read April issue @TrendsImmuno: #immunity #pain #IBS, #liver #metastasis responsiveness, #tumor #neoantigens, #glioblastoma #macrophage/#microglia, #cytokines & #checkpoint #toxicity, #IFN & #SARSCoV2, #leukocytes & #lamins, #Bcl6 & #Tfh, #ATM & immunity!! https://t.co/yJe57PKnW3 https://t.co/ipv8Ee6tzn
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Mashup Score: 0Cancer and Its Treatment May Have Consequences for Survivors’ Ability to Work, Says New Report | National Academies - 3 year(s) ago
Although cancer survivors are living longer, cancer and its treatment can result in long-lasting or late-onset impairments that may affect their ability to work, says a new report from the National Academies of Sciences, Engineering, and Medicine.
Source: www.nationalacademies.orgCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 2The Vexed Problem of Corticosteroid Toxicity in Asthma: Time for Standardized Assessment - 3 year(s) ago
The systemic toxicity from inhaled corticosteroids (ICS) in adult asthma has long been considered an inevitable and justifiable consequence of attempting to obtain optimal asthma control and reduce the risk of severe exacerbations, including mortality. Although the widespread use of ICS has contributed to the marked global reduction in asthma mortality since the 1990s,1 there is increasing…
Categories: Allergy-Immunology, Latest HeadlinesTweet
Been meaning to look up the #toxicity grading for dry mouth for a while in the context of the #VISION (#Lu-177 trial) in #mCRPC #ProstateCancer It certainly adds an important understanding to the grade 1-2 Dry mouth reported in this and future trials https://t.co/NjjAxMasAs https://t.co/hKLQPGBCiN