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Mashup Score: 2
In older patients with cancer, it is very important to choose the appropriate treatment because they are at high risk for chemotherapy toxicity. Our study investigated characteristics of Cancer and Aging Research Group (CARG), Geriatric 8 (G8), and Vulnerable Elders Survey (VES-13) screening tools for predicting chemotherapy-related toxicity (CRT) prospectively.
Source: Journal of Geriatric OncologyCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0Lack of Concordance in Symptomatic Adverse Event Reporting by Children, Clinicians, and Caregivers: Implications for Cancer Clinical Trials - 2 year(s) ago
PURPOSE To examine concordance in symptomatic adverse event (AE) grading using the Common Terminology Criteria for Adverse Events (CTCAE 4.0) for clinicians and its patient-reported outcome (PRO) versions for children (Ped-PRO-CTCAE) and caregivers (Ped-PRO-CTCAE [Caregiver]). METHODS Children age 7-18 years with a first cancer diagnosis, their clinicians, and caregivers completed CTCAE-based…
Source: Journal of Clinical OncologyCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
🤕 Clinicians often underestimate symptomatic adverse events reported by children treated for cancer. 👏👏👏Call to action for use of #PROS routinely to grade #toxicity ➡️ https://t.co/S5X3ZtrWU0 #JCO #pedcsm https://t.co/JmxPfqZVVi
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Mashup Score: 0
A newly designed model will outline what genetic patterns put men with prostate cancer at an increased risk of toxic side effects.
Source: Oncology Nursing NewsCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
DNA linked to genitourinary toxicity risk with radiation in prostate cancer #pcsm #toxicity https://t.co/vLUZuZwSy9
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Mashup Score: 3
Timing chemotherapy on the basis of the body’s intrinsic circadian clock—ie, chronomodulated chemotherapy—might improve efficacy and reduce treatment toxicity. This systematic review summarises the available clinical evidence on the effects of chronomodulated chemotherapy from randomised, controlled trials in adult patients with cancer, published between the date of database inception and June 1,…
Source: The Lancet OncologyCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
NEW Review: #Toxicity and #efficacy of #chronomodulated #chemotherapy: a systematic review https://t.co/SmdyjgT3YC
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Mashup Score: 1
By Matthew Stenger Posted: 2/15/2022 12:24:00 PM Last Updated: 2/15/2022 2:34:22 PM In a study reported in the Journal of Clinical Oncology, Joseph M. Unger, PhD, and colleagues found that women in clinical trials of chemotherapy, immunotherapy, or targeted therapy had a…
Source: ascopost.comCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
Differences in Risk of Severe Adverse Events in Women vs Men Receiving Immunotherapy, Targeted Therapy, or Chemotherapy in Cancer Clinical Trials https://t.co/5ioqGuRobM #toxicity #clinicaltrials #immunotherapy #chemotherapy #targetedtherapy
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Mashup Score: 0Dr. Kishan calls for more prospective studies on the predictive nature of germline variants - 2 year(s) ago
“What really needs to be done to show that this works is to look prospectively,” says Amar U. Kishan, MD.
Source: Urology TimesCategories: Latest Headlines, UrologyTweet-
Dr. Kishan discusses takeaways of a recent study on the association between germline variants and GU toxicity https://t.co/87hoOo7v6U #ProstateCancer #Toxicity #GermlineVariants #Urology #Urologist
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Mashup Score: 0
Patients were followed for a median of two-years. Those treated with SBRT showed no difference in hazard of any cardiovascular outcomes by tumor laterality including the cardiovascular composite (hazard ratio comparing left versus right-sided tumors [HR]=0.98, 95% confidence interval [CI]=0.84-1.15) …
Source: PubMedCategories: Latest Headlines, PulmonologyTweet-
Risk of #Cardiovascular #Toxicity According to Tumor #Laterality Among #Older #Early #Stage #Non- #small #Cell #Lung #Cancer Patients Treated with #Radiation #Therapy #NSCLC https://t.co/4PcoGQQPed https://t.co/YGIdNFckwb
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Mashup Score: 3Dangers of hyperoxia - Critical Care - 2 year(s) ago
Oxygen (O2) toxicity remains a concern, particularly to the lung. This is mainly related to excessive production of reactive oxygen species (ROS). Supplemental O2, i.e. inspiratory O2 concentrations (FIO2) > 0.21 may cause hyperoxaemia (i.e. arterial (a) PO2 > 100 mmHg) and, subsequently, hyperoxia (increased tissue O2 concentration), thereby enhancing ROS formation. Here, we review the…
Source: BioMed CentralCategories: Critical Care, Latest HeadlinesTweet-
#CritCare #OpenAccess Insights in the #pathophysiology of #O2 #toxicity and the potential harms of supplemental O2 in various #ICU conditions https://t.co/5qJLY4X7qx @jlvincen @ISICEM #FOAMed #FOAMcc #BMC #ICU #lung #Hyperoxia #Hyperoxaemia #TBI #stroke #resuscitation #sepsis https://t.co/oJzYrSSMmT
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Mashup Score: 0
Objectives This study aims at exploring and quantifying multiple types of adverse events (AEs) experienced by patients during cancer treatment. A novel longitudinal score to evaluate the Multiple Overall Toxicity (MOTox) burden is proposed. The MOTox approach investigates the personalised evolution of high overall toxicity (high-MOTox) during the treatment. Design Retrospective analysis of the…
Source: BMJ OpenCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
Novel #longitudinal Multiple Overall #Toxicity (MOTox) score to quantify adverse events experienced by patients during #chemotherapy treatment: a retrospective analysis of the MRC BO06 trial in osteosarcoma https://t.co/S07hbYHaIM https://t.co/ODS1szjEG0
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Mashup Score: 24Sacituzumab Govitecan for Metastatic Triple‐Negative Breast Cancer: Clinical Overview and Management of Potential Toxicities - 2 year(s) ago
The Oncologist is committed to helping physicians excel in the constantly changing fields of oncology and hematology through the publication of timely reviews, original studies, and commentaries on important developments.
Source: The OncologistCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
Sacituzumab Govitecan for Metastatic Triple‐Negative Breast Cancer: Clinical Overview and Management of Potential Toxicities #BreastCancer #Therapeutics #AntibodyDrugConjugates #Toxicity https://t.co/ppG6kVYIXO https://t.co/QcUCK61JpF
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Prospective comparison of the value of CARG, G8, and VES-13 toxicity tools in predicting chemotherapy-related toxicity in older Turkish patients with cancer https://t.co/g5riZRxR7e @WilliamDale_MD @rochgerionc @myCARG #GeriOnc #OlderAdults #OncoAlert #YoungSIOG #Toxicity https://t.co/OlhXnSEBjp