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Mashup Score: 9Association of Lipopolysaccharide-Type Endotoxins with Retinal Neurodegeneration: The Alienor Study - 9 month(s) ago
Lipopolysaccharide (LPS)-type endotoxins are naturally found in the gut microbiota and there is emerging evidence linking gut microbiota and neuroinflammation leading to retinal neurodegeneration. Thinning of the retinal nerve fiber layer (RNFL) is a biomarker of retinal neurodegeneration, and a hallmark of glaucoma, the second leading cause of blindness worldwide. We assessed the association of a blood biomarker of LPS with peripapillary RNFL thickness (RNFLT) and its longitudinal evolution up to 11 years.
Source: www.ophthalmologyscience.orgCategories: General Medicine News, OphthalmologyTweet
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Mashup Score: 2Labcorp Launches New Amyloid-Tau-Neurodegeneration Biomarker Blood Test - Practical Neurology - 2 year(s) ago
Labcorp has announced that its ATN Profile (Laboratory Corporation of America Holdings, Burlington, NC) test for identifying and assessing biological
Source: practicalneurology.comCategories: Latest Headlines, NeurologyTweet-
To reduce time to #Alzheimer disease diagnosis, HCPs can now order the #ATN Profile test from @Labcorp, which measures changes in #amyloid plaques, #tau tangles, and #neurodegeneration/#NeurofilamentLightChain biomarkers. https://t.co/zE1lggNuH1
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Mashup Score: 1Similarities and Differences Between Cellular and Molecular Mechanisms of Normal Brain Aging and Neurodegeneration - 2 year(s) ago
Currently, mankind has succeeded in increasing life expectancy above 60 years worldwide, with even more impressive achievements in developed countries, such as Japan (over 82 years), Australia (over 80 years), or Europe. However, this increase is at the expense of the increased prevalence of neurodegenerative diseases, especially dementia.Aging is an inherent process in all living organisms, and…
Source: FrontiersCategories: Latest Headlines, NeurologyTweet-
Researching the Mechanisms of Brain Aging? Why not take a look at the new topic in Frontiers in Aging Neuroscience, open for papers NOW! To register your interest or find out more, follow this link: https://t.co/V2Rhd0EcRv #research #neurodegeneration #submissions #OpenAccess https://t.co/IJF2jydoHo
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Mashup Score: 0How we sweep while we sleep - from basic research to clinical implications of the glymphatic system - eanpages - 2 year(s) ago
Report on Symposium 3 at EAN 2023 – ‘Clearing the brain at night: Glymphatics, sleep and neurodegeneration’.
Source: eanpagesCategories: Latest Headlines, NeurologyTweet-
The symposium at #ean2023 on the #glymphatic system, sleep and #neurodegeneration opened exciting new possibilities for future treatments, linking sleep quality and brain clearance to potentially modify a range of neurological diseases. Full article 👉 https://t.co/HpWanKu1wu
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Mashup Score: 0AI helps show how the brain's fluids flow: New research targets diseases including Alzheimer's - 2 year(s) ago
A new, AI-based technique for measuring fluid flow in the brain could lead to treatments for diseases such as Alzheimer’s.
Source: ScienceDailyCategories: Healthcare Professionals, Latest HeadlinesTweet-
#AI helps show how the #brain's fluids flow: New research targets diseases including #Alzheimer's https://t.co/PADdRjvJAb @PNASNews #CSF #glymphatic #velocimetry #stroke #aging #neurodegeneration HT @NitaFarahany "The pressure is important because nobody knows for sure quite… https://t.co/msFuwo92Tv https://t.co/ffYsTqt4Ij
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Mashup Score: 2Molecular and Cellular pathways leading to Mitochondrial Dysfunction and Neurodegeneration: Lessons from in vivo models - Volume II - 2 year(s) ago
This Research Topic is the second volume of Research Topic
Source: FrontiersCategories: Latest Headlines, NeurologyTweet-
🚨Do not miss out on the chance to share the latest insights and advancements in Volume II of this Frontiers in Neuroscience Research Topic! 🗓️Deadlines🗓️ Abstract: 31 May Manuscript: 31 October Make your contribution➡️https://t.co/18ii4Jldux #mitochondria #neurodegeneration https://t.co/Qon4WNHnKU
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Mashup Score: 4Second Patient with Extremely Rare Genetic Resistance to Alzheimer’s Disease Discovered - 2 year(s) ago
Among an autosomal dominant Alzheimer’s disease cohort, the patient carried an additional, rare gain-of-function variant.
Categories: Future of Medicine, Latest HeadlinesTweet-
One amino acid swap due to a rare variant in a Colombian person could potentially steer the course of therapeutic strategies for diseases with #neurodegeneration and #dementia, such as #Alzheimersdisease. Learn more: https://t.co/8YOLYWi8Nq https://t.co/XQ9MyVIRI0
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Mashup Score: 1A new peptide may hold potential as an Alzheimer’s treatment - 2 year(s) ago
MIT neuroscientists found a way to reverse neurodegeneration and other symptoms of Alzheimer’s disease in mice by using a peptide to interfere with an enzyme that is typically overactive in the brains of Alzheimer’s patients.
Categories: Healthcare Professionals, Latest HeadlinesTweet-
A new peptide may hold potential as an #Alzheimer’s treatment https://t.co/35a7drW0K8 #dementia #neurodegeneration #Cdk5i #tau #BBB A #Cdk5-derived [12-AA] peptide inhibits Cdk5/#p25 activity and improves neurodegenerative phenotypes | PNAS https://t.co/82Ru6NrEjj https://t.co/ElHmfAs0vy
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Mashup Score: 0Neurodegenerative Diseases, Metabolic Syndrome and Lipid Rafts: Endogenous Stressors, Adipokines and Their Regulation by Nutrition - 2 year(s) ago
Metabolic syndrome and obesity involve dysregulation of adipokines (leptin, adiponectin) and hyperglycemia caused by the gradual development of insulin resistance and type 2 diabetes. Recently, progranulin has also been described as an adipokine involved in insulin signaling. Adipokines are particularly regulated by the intake of fat, and different types of fat have an impact on lipid rafts,…
Source: FrontiersCategories: Latest Headlines, NeurologyTweet-
🚨Deadline extended🚨 Last chance to get involved in this exciting Research Topic led by Johanna Ojala, Ana Ledo and Jennifer Griffin via Frontiers in Neuroscience 🗓️Deadline: 15 April 2023 Submit today▶️https://t.co/wmyLHy0tAM #lipidrafts #neurodegeneration #metabolism https://t.co/ocXUqP1PDd
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Mashup Score: 0
17 Mar 2023 Here’s a tau twist that may take some adapting to. CD4+ and CD8+ T cells, yes, those mercurial executioners of the immune system, may be responsible for the neurodegeneration seen in Alzheimer’s disease and other tauopathies. That’s the scenario outlined by David Holtzman, Washington University, St. Louis, and colleagues in Nature on March 8. The scientists report that,…
Source: www.alzforum.orgCategories: Healthcare Professionals, Latest HeadlinesTweet-
#Neurodegeneration—It’s Not the Tangles, It’s the #TCells https://t.co/571GEFzpMZ #microglia #CD8+ #meninges #brain #parenchyma #immunity #PD1 #dementia #amyloid #tau #Aβ Activated immune cells drive neurodegeneration in an #Alzheimer’s model https://t.co/VUaJjzkPk7 Can #AD… https://t.co/UGZigewVsm https://t.co/3BL4qnK4CR
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1 SD increase in Plasma esterified 3-hydroxy fatty acids (proxy for LPS-type endotoxins) was assc w/ 1.4 micron decrease in avg RNFL thickness measured by SD-OCT in 1062 eyes of 548 people indicating role of gut microbiome in #neurodegeneration. https://t.co/Iru3HqfB0u https://t.co/LT2ceYV7Ye