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    Worse long-term renal outcome of lupus nephritis patients of African descent living in Europe - 2 year(s) ago

    Introduction Prognosis of lupus nephritis (LN) among patients of African descent living in Europe has been understudied. Methods In a retrospective study performed in two European university hospitals, we compared the prognosis of LN in patients of African descent or Caucasians. Remission was defined as a urine protein to creatinine (uP/C) ratio<0.5 g/g and a serum creatinine value<120% of...

    Source: RMD Open
    Categories: Latest Headlines, Rheumatology
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      ARD_BMJ

      Retrospective study in people with #Lupus #nephritis Different outcomes comparing African descent (Ad) living in Europe and Caucasians? - similar remission rates after initial treatment & adherence - subsequent renal flares more frequent --> more CKD in Ad https://t.co/pDyyaogilO https://t.co/w1pMeWJCQa

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    Lupus nephritis - Nature Reviews Disease Primers - 2 year(s) ago

    Lupus nephritis is an inflammation of the kidneys caused by the autoimmune disease systemic lupus erythematosus. This Primer reviews the epidemiology of lupus nephritis, its pathogenesis and advances in its treatment.

    Source: Nature
    Categories: Latest Headlines, Rheumatology
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      NatRevRheumatol

      Insightful session on #Nephritis this morning at #lupus2022 For some extra reading, check out this Primer on #LupusNephritis by @hjanders_hans and colleagues in our sister journal @DiseasePrimers https://t.co/Wgl6MjICFX

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    Urinary HER2, TWEAK and VCAM-1 levels are associated with new-onset proteinuria in paediatric lupus nephritis - 2 year(s) ago

    Objective Lupus nephritis is a key driver of morbidity and mortality in SLE. Detecting active nephritis on a background of pre-existing renal damage is difficult, leading to potential undertreatment and accumulating injury. An unmet need is a biomarker that distinguishes active lupus nephritis, particularly important in paediatrics where minimising invasive procedures is desirable. Methods This…

    Source: Lupus Science & Medicine
    Categories: Latest Headlines, Rheumatology
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      Lupus_SM

      #Lupusnephritis This week on LSM: Study identified #biomarkers in #urine that could be used in a point-of-service test to identify a #flare of #lupus #nephritis or an impending flare of #SLE nephritis https://t.co/4ZSrJ07hjU

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    Urinary HER2, TWEAK and VCAM-1 levels are associated with new-onset proteinuria in paediatric lupus nephritis - 2 year(s) ago

    Objective Lupus nephritis is a key driver of morbidity and mortality in SLE. Detecting active nephritis on a background of pre-existing renal damage is difficult, leading to potential undertreatment and accumulating injury. An unmet need is a biomarker that distinguishes active lupus nephritis, particularly important in paediatrics where minimising invasive procedures is desirable. Methods This…

    Source: Lupus Science & Medicine
    Categories: Latest Headlines, Rheumatology
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      Lupus_SM

      #Lupusnephritis This week on LSM: Study identified #biomarkers in #urine that could be used in a point-of-service test to identify a #flare of #lupus #nephritis or an impending flare of #SLE nephritis https://t.co/4ZSrJ07hjU

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    Urinary HER2, TWEAK and VCAM-1 levels are associated with new-onset proteinuria in paediatric lupus nephritis - 2 year(s) ago

    Objective Lupus nephritis is a key driver of morbidity and mortality in SLE. Detecting active nephritis on a background of pre-existing renal damage is difficult, leading to potential undertreatment and accumulating injury. An unmet need is a biomarker that distinguishes active lupus nephritis, particularly important in paediatrics where minimising invasive procedures is desirable. Methods This…

    Source: Lupus Science & Medicine
    Categories: Latest Headlines, Rheumatology
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    • Profile photo of Lupus_SM
      Lupus_SM

      #Lupusnephritis This week on LSM: Study identified #biomarkers in #urine that could be used in a point-of-service test to identify a #flare of #lupus #nephritis or an impending flare of #SLE nephritis https://t.co/4ZSrJ07hjU

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    Research in Brief - 2 year(s) ago

    David Jayne and colleagues conducted a phase 2 trial to assess the safety and efficacy of the type I interferon receptor inhibitor anifrolumab in patients with active lupus nephritis. 147 patients were randomly assigned (1:1:1) to receive 300 mg intravenous anifrolumab (the basic regimen), an intensified anifrolumab regimen consisting of three 900 mg doses followed by 300 mg thereafter, or…

    Source: The Lancet Rheumatology
    Categories: Latest Headlines, Rheumatology
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      TheLancetRheum

      April Research in Brief featuring #lupus #nephritis, #polymyalgia rheumatica, #osteoarthritis, and more! https://t.co/kQ6xl3Pl9y #LancetRheumatology https://t.co/3T7o5koZfT

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