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Mashup Score: 6Frequency of New or Enlarging Lesions on MRI Outside of Clinical Attacks in Patients With MOG-Antibody–Associated Disease - 2 year(s) ago
Background and Objective To determine the frequency of new or enlarging T2-hyperintense or enhancing lesions outside of clinical attacks in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD) vs multiple sclerosis (MS) and aquaporin-4 antibody positive neuromyelitis optica spectrum disorder (AQP4+NMOSD). Methods We retrospectively included Mayo Clinic patients with MOGAD…
Source: NeurologyCategories: Latest Headlines, NeurologyTweet
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Mashup Score: 0Area Postrema Syndrome - 2 year(s) ago
Objectives Area postrema syndrome (APS) is one of the core clinical features of neuromyelitis optic spectrum disorder (NMOSD). APS is mostly associated with neuromyelitis optica (NMO) and rarely reported in myelin oligodendrocyte glycoprotein antibody disease. We herein report a case of APS as an initial presentation of double-seropositive aquaporin-4 and myelin oligodendrocyte glycoprotein (MOG)…
Source: Neurology Clinical PracticeCategories: Latest Headlines, NeurologyTweet
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Mashup Score: 0Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease Presenting as Intracranial Hypertension - 2 year(s) ago
The production of autoantibodies against myelin oligodendrocyte glycoprotein (MOG) can cause a spectrum of autoimmune disorders, including optic neuritis, transverse myelitis, brainstem encephalitis, and acute disseminated encephalomyelitis. In this study, we present the case of a 19-year-old woman with an unusual clinical presentation of intracranial hypertension (IH) and bilateral papilledema….
Categories: Latest Headlines, NeurologyTweet-
In this study, Chaudhuri et al. report an unusual manifestation of myelin oligodendrocyte glycoprotein antibody-associated disease (#MOGAD) in a young woman who presented with isolated intracranial hypertension. Read the open access article: https://t.co/i5gryeUpYN #NeuroTwitter https://t.co/H243BSFxLf
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Mashup Score: 4Temporal Dynamics of MOG Antibodies in Children With Acquired Demyelinating Syndrome - 2 year(s) ago
Background and Objective The spectrum of myelin oligodendrocyte glycoprotein (MOG) antibody–associated disorder (MOGAD) comprises monophasic diseases such as acute disseminated encephalomyelitis (ADEM), optic neuritis (ON), and transverse myelitis and relapsing courses of these presentations. Persistently high MOG antibodies (MOG immunoglobulin G [IgG]) are found in patients with a relapsing…
Categories: Latest Headlines, NeurologyTweet
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Mashup Score: 9Differentiating Multiple Sclerosis From AQP4-Neuromyelitis Optica Spectrum Disorder and MOG-Antibody Disease With Imaging - 2 year(s) ago
Background and objectives: Relapsing remitting multiple sclerosis (RRMS), aquaporin4 antibody-positive neuromyelitis optica spectrum disorder (AQP4-NMOSD) and myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) may have overlapping clinical features. There is an unmet need for imaging markers that differentiate between them when serologic testing is unavailable or ambiguous….
Source: NeurologyCategories: Latest Headlines, NeurologyTweet
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Mashup Score: 0Optic neuritis and autoimmune optic neuropathies: advances in diagnosis and treatment - 2 year(s) ago
Optic neuritis is an inflammatory optic neuropathy that is commonly indicative of autoimmune neurological disorders including multiple sclerosis, myelin-oligodendrocyte glycoprotein antibody-associated disease, and neuromyelitis optica spectrum disorder. Early clinical recognition of optic neuritis is important in determining the potential aetiology, which has bearing on prognosis and treatment….
Source: The Lancet NeurologyCategories: Latest Headlines, NeurologyTweet-
In the second Review in the Series, Jeffrey Bennett and colleagues discuss advances in diagnosis and treatment of optic neuritis and autoimmune optic neuropathies, and suggest the optic nerve should be included in the McDonald criteria #MS #MOGAD #NMOSD https://t.co/wWKbNFQqaB https://t.co/WqY0iTiLIZ
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Mashup Score: 0Europe Support Group Meeting - 2 year(s) ago
Join us for an online support group meeting hosted by Pilar Schnadenberger, one of our Europe Support Group Leaders, who is based in Germany!
Source: SRNACategories: Latest Headlines, Rare DiseaseTweet
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Mashup Score: 3Wolters Kluwer Health - 2 year(s) ago
JavaScript Error JavaScript has been disabled on your browser. You must enable it to continue. Here’s how to enable JavaScript in the following browsers: Internet Explorer From the Tools menu, select Options Click the Content tab Select Enable…
Source: lww.comCategories: Latest Headlines, NeurologyTweet
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Mashup Score: 3MOGAD Awareness Virtual Event - 2 year(s) ago
Join us for a special virtual event in recognition of MOGAD Awareness Month, in partnership with The MOG Project, The Sumaira Foundation for NMO, and The Guthy-Jackson Charitable Foundation.
Source: SRNACategories: Latest Headlines, Rare DiseaseTweet
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Mashup Score: 3Aseptic Meningitis Followed by Bilateral Optic Neuritis - 2 year(s) ago
MOGAD should be considered in patients with aseptic meningitis without encephalitis when the infective etiology has been excluded. Because they merit long-term management and follow-up evaluation, repeat testing with MOG antibody is essential.
Source: Neurology Clinical PracticeCategories: Latest Headlines, NeurologyTweet
This study found new or enlarging lesions outside of attacks rarely developed on surveillance brain MRI in #MOGAD differing from #MS. Read the open access article: https://t.co/inMP11cMeL #NeuroTwitter https://t.co/b7GzrTDby8