• Mashup Score: 4

    The first insulin preparation capable of consistently lowering blood glucose was developed in 1921. But 100 years later, blood glucose control with insulin in people with diabetes is nearly universally suboptimal, with essentially the same molecule still delivered by the same inappropriate subcutaneous injection route. Bypassing this route with oral administration appears to have become…

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  • Mashup Score: 5

    Before 1921 the diagnosis of diabetes was a death sentence, with an average life expectancy of less than 2 years in young people, who were only kept alive by a starvation regimen that reduced them to walking skeletons.1 The discovery of insulin in 1921 was transformative and many patients with diabetes went on to live full and productive lives.

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    • The demands of self-managing type 1 diabetes can take their toll. Despite technological advances, a quality partnership between patient & health professional remains central to treatment. @simonrheller #Insulin100 https://t.co/zYjdMwqt0L

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    Diabetes is a global epidemic. Today, approximately 6% of the world’s population—more than 420 million people—live with either type 1 or type 2 diabetes. This number has quadrupled since 1980, and is estimated to rise beyond half a billion by the end of the decade. Whereas premature mortality from other major non-communicable diseases is decreasing, early deaths from diabetes have actually…

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    100 years of Insulin - 3 year(s) ago

    2021 marks 100 years since the discovery of #insulin. Watch our #EASD2021 mini-documentary to learn more about the history of this discovery, which has saved…

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    • Today is #WorldDiabetesDay - take a moment to watch our fascinating short film looking at the history behind the discovery of #insulin 👇 #Insulin100 #diabetes #DiabetesAwarenessMonth #T1D #WDD2021 https://t.co/ESuf7QwRbK

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    “I need to be blunt: the world is on the brink of a catastrophic moral failure—and the price of this failure will be paid with lives and livelihoods in the world’s poorest countries.”1 This statement, from WHO Director-General Tedros Adhanom Ghebreyesus, made as he opened the annual WHO Executive Board meeting in January, 2021, concerned the inadequate access to COVID-19 vaccines for low-income…

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    • Failing to address #access to #insulin in its #centenary year would be a catastrophic moral failure https://t.co/B32YxGMiCN #Insulin100 #InsulinCentenary #Insulin4all #WorldDiabetesDay2021 #IfNotNowWhen #FREE to read with registration (also FREE)

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    100 years of insulin - 3 year(s) ago

    100 years ago, insulin was discovered. Today, it is still inaccessible for millions. What were the events that led to the discovery of insulin and turned it into the first life-saving treatment for diabetes? What are the challenges in closing the gap in global access to insulin? What does the…

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    • Visit the 100 years of #insulin Hub for content from across the Lancet journals https://t.co/Z5lJXKHpFe #Insulin100 #InsulinCentenary #Insulin4all #diabetes #WorldDiabetesDay2021 #IfNotNowWhen https://t.co/S7j35RWWyY

  • Mashup Score: 4

    At 2:00 h on Oct 31, 1920, Frederick G Banting, a surgeon practising in London, ON, Canada, conceived an idea to isolate the internal secretion of the pancreas. The following week, he met with noted scientist John J R Macleod in Toronto, ON, Canada, and they developed a research plan. By August, 1921, Banting and his student assistant Charles H Best had prepared an effective extract from a canine…

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    • RT @TheLancetEndo: Insulin's centenary: the birth of an idea https://t.co/JsYkX1vgNE #insulin #Insulin100 #InsulinCentenary #diabetes #Worl…