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Mashup Score: 0
Scientists are deciphering how the brain choreographs immune responses, hoping to find treatments for a range of diseases.
Source: www.nature.comCategories: Healthcare Professionals, Latest HeadlinesTweet
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Mashup Score: 0
Skip Nav Destination January 26, 2023 In patients with activated phosphoinositide 3-kinase delta (PI3Kδ) syndrome (APDS), the use of the oral PI3Kδ inhibitor leniolisib reduced lymphadenopathy and normalized immune cell subsets,…
Source: ashpublications.orgCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 0Long-term immune reconstitution in ADA-deficient patients treated with elapegademase: a real-world experience. - 2 year(s) ago
ADAGEN®, a bovine-based enzyme replacement therapy (ERT) has been used to treat adenosine deaminase severe combined immune deficiency (ADA-SCID). In 2018, ADAGEN® was replaced by REVCOVI®, (elapegademase) a modified bovine recombinant protein.
Categories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 0
Background Mortality prediction for intensive care unit (ICU) patients frequently relies on single acuity measures based on ICU admission physiology without accounting for subsequent clinical changes. Objectives Evaluate novel models incorporating modified admission and daily, time-updating Laboratory-based Acute Physiology Scores, version 2 (LAPS2) to predict in-hospital mortality among ICU…
Source: medRxivCategories: Latest Headlines, PulmonologyTweet
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Mashup Score: 2Immune 64: A tangled web of wires - 2 year(s) ago
Cindy, Steph, Brianne, and Vincent do a rapid review of 11 immunology papers, including a wiring diagram for the immune system, group A streptococcus vaccines, systems immunology prediction of vaccines, class switch towards IgG4 after SARS-CoV-2 mRNA vaccination, very bad B cells, monoclonal antibody to two streptococcal M protein epitopes, transcriptional atlas of response to 13 vaccines, impact…
Categories: Infectious Disease, Latest HeadlinesTweet
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Mashup Score: 5
Immune checkpoint-inhibitors (ICIs) are changing outcomes in different cancer settings, notably for patients with non-small-cell lung cancer (NSCLC). There are, however, still important gaps of evidence for clinical practice when using these novel treatments. In this study, we assessed physicians’ opinion and experience on challenges for clinical practice with ICIs monotherapy in NSCLC.
Source: Esmo OpenCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 6Germline genetic contribution to the immune landscape of cancer - 2 year(s) ago
Sayaman, Saad et al. investigate the effect of common and rare germline variants on 139 well-defined immune traits in ∼9000 cancer patients enrolled in TCGA, providing evidence for the impact of germline genetics on the composition and functional orientation of the tumor immune microenvironment.
Source: ImmunityCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 3Germline genetic contribution to the immune landscape of cancer - 2 year(s) ago
Sayaman, Saad et al. investigate the effect of common and rare germline variants on 139 well-defined immune traits in ∼9000 cancer patients enrolled in TCGA, providing evidence for the impact of germline genetics on the composition and functional orientation of the tumor immune microenvironment.
Source: ImmunityCategories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 1The Immune Profile of Merkel Cell Carcinoma - 2 year(s) ago
New clues about the immune system response to MCC may be able to help guide future treatment strategies.
Source: Dermatology TimesCategories: Dermatology, Latest HeadlinesTweet
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Mashup Score: 0
Asthma and obesity are both complex conditions characterized by chronic inflammation, and obesity-related severe asthma has been associated with differences in the microbiome. However, whether the airway microbiome and microbiota-immune response relationships differ between obese persons with or without non-severe asthma is unestablished.
Categories: Latest Headlines, PulmonologyTweet
🧠🔥Your #brain could be controlling how sick you get — and how you recover @Nature Scientists are deciphering how the brain choreographs #immune responses, hoping to find #treatments for a range of #diseases. #science #research @EvanKirstel https://t.co/IjcxfmsMbw… https://t.co/fi71p6gjwZ