-
Mashup Score: 6
Objective Braak’s hypothesis states that Parkinson’s disease (PD) originates in the gastrointestinal (GI) tract, and similar associations have been established for Alzheimer’s disease (AD) and cerebrovascular diseases (CVD). We aimed to determine the incidence of GI syndromes and interventions preceding PD compared with negative controls (NCs), AD and CVD. Design We performed a combined case-control and cohort study using TriNetX, a US based nationwide medical record network. Firstly, we compared subjects with new onset idiopathic PD with matched NCs and patients with contemporary diagnoses of AD and CVD, to investigate preceding GI syndromes, appendectomy and vagotomy. Secondly, we compared cohorts with these exposures to matched NCs for the development of PD, AD and CVD within 5 years. Results We identified 24 624 PD patients in the case-control analysis and matched 18 cohorts with each exposure to their NCs. Gastroparesis, dysphagia, irritable bowel syndrome (IBS) without diarrhoea
Source: gut.bmj.comCategories: General Medicine News, Latest HeadlinesTweet
-
Mashup Score: 0Viome scores $86.5M and launches gut test into CVS - 9 month(s) ago
The life sciences company’s Gut Intelligence Test will be available in 200 CVS locations and through the drug store chain online.
Source: www.mobihealthnews.comCategories: Healthcare Professionals, Latest HeadlinesTweet
-
Mashup Score: 21
Regular consumption of lacto-fermented vegetables has greater effects on the gut metabolome compared with the microbiome – Volume 4
Source: www.cambridge.orgCategories: General Medicine News, Latest HeadlinesTweet
-
Mashup Score: 0Kenneth Croitoru and Williams Turpin on Dietary Patterns and Intestinal Inflammation - 10 month(s) ago
Recent years have seen mounting interest in the impact of diet on the gut microbiome, gastrointestinal inflammation, and the development of inflammatory bowel diseases. To investigate the connection between diet and gut inflammation, the study group known as the Crohn’s and Colitis Canada Genetic, Environmental, Microbial Project Research Consortium recruited a large cohort of healthy first-degree relatives of patients with Crohn’s disease (CD).
Source: www.medpagetoday.comCategories: General Medicine News, Latest HeadlinesTweet
-
Mashup Score: 0Are Probiotic Drinks Really Good For You? - 10 month(s) ago
Probiotic drinks—like yogurt and kombucha—are all the rage. But the benefits may not live up to the buzz.
Source: www.henryford.comCategories: General Medicine News, Latest HeadlinesTweet
-
Mashup Score: 2A roadmap for gut microbiome-derived aromatic amino acids for improved cardiovascular risk stratification - 10 month(s) ago
This editorial refers to ‘Atlas of gut microbe-derived products from aromatic amino acids and risk of cardiovascular morbidity and mortality’, by I. Nemet et al
Source: OUP AcademicCategories: Cardiologists, Latest HeadlinesTweet
-
Mashup Score: 6The impact of metabolic endotoxaemia on the browning process in human adipocytes - BMC Medicine - 12 month(s) ago
Background Dysfunctional adipose tissue (AT) is known to contribute to the pathophysiology of metabolic disease, including type 2 diabetes mellitus (T2DM). This dysfunction may occur, in part, as a consequence of gut-derived endotoxaemia inducing changes in adipocyte mitochondrial function and reducing the proportion of BRITE (brown-in-white) adipocytes. Therefore, the present study investigated…
Source: BioMed CentralCategories: General Medicine News, Latest HeadlinesTweet
-
Mashup Score: 28Home - The Gastrointestinal Epithelium Conference: Interface with the Outside World - 12 month(s) ago
This is a sample of an event description that might display in Google.
Source: web.cvent.comCategories: Hem/Oncs, Latest HeadlinesTweet
-
Mashup Score: 3Mendelian Randomization analyses identify causal associations of human gut microbiome composition on intelligence - 12 month(s) ago
Background Growing evidence indicates that dynamic changes in the gut microbiome can affect intelligence; however, whether the relationships are causal is unknown. Methods We conducted a bidirectional two-sample Mendelian randomization (MR) analysis using the summary statistics from the largest GWAS meta-analysis of gut microbiota composition (n = 18,340) and intelligence (n = 269,867)….
Source: medRxivCategories: Healthcare Professionals, Latest HeadlinesTweet
-
Mashup Score: 0Common Gut Bacteria Linked to Parkinson's Disease - 12 month(s) ago
Desulfovibrio, a common gut bacteria, may play a role in the development of Parkinson’s disease by causing aggregation of the alpha-synuclein protein.
Source: MedscapeCategories: Healthcare Professionals, Latest HeadlinesTweet
Certain #gut conditions may be early warning signs of #Parkinson'sdisease https://t.co/TCzEhsAmTr https://t.co/go3vAuuEBT