• Mashup Score: 1

    A microdevice has been designed that can be implanted into tumors to conduct dozens of experiments at once to study the effects of new treatments on some of the hardest-to-treat brain cancers.

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    • WOW: #Microdevices implanted into #tumors offer new way to treat #braincancer https://t.co/z877OzCnsq via @Harvard Intratumoral drug-releasing microdevices allow in situ high-throughput pharmaco #phenotyping in patients with #gliomas https://t.co/nRD1Ik0KM6 @ScienceTM #glioma… https://t.co/0XvN7kwCxv https://t.co/Pparl9R3cX

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    Summary:. Pediatric high-grade gliomas represent a group of deadly, heterogeneous tumors, often driven by histone mutations and the accumulation of clonal mutations, correlating with different tumor types, locations, and age of onset. In this study, McNicholas and colleagues present 16 in vivo models of histone-driven gliomas to investigate subtype-specific tumor biology and treatment options.See related article by McNicholas et al., p. 1592 (7).

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    • #ICYMI from the July issue— In the Spotlight: Modeling the landscape of histone-mutant pediatric-high grade #gliomas: A study in partner alterations, by Evan Lubanszky and @CHawkinsLab. https://t.co/SF0y49IQzx @SickKidsNews @UofT https://t.co/30bAExzFdQ

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    Vorasidenib (AG-881) is a promising targeted therapy for gliomas with IDH1 or IDH2 mutations. This novel approach could potentially revolutionize glioma treatment, reducing side effects and improving outcomes. Gliomas, specifically Grade 2 gliomas, are a complex group of brain tumors with varying prognoses dependi…

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    • Exciting advancements in oncology! AG-881 (Vorasidenib) is a potential game-changer in treating #gliomas, a type of #braintumor Read our in-depth article with an interview with Karan Dixit, MD, during #ASCO23. @NorthwesternMedicine https://t.co/P7uZQ4tby4

  • Mashup Score: 0
    Wolters Kluwer Health - 10 month(s) ago

    JavaScript Error JavaScript has been disabled on your browser. You must enable it to continue. Here’s how to enable JavaScript in the following browsers: Internet Explorer From the Tools menu, select Options Click the Content tab Select Enable JavaScript Firefox From the Tools…

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    • “H3K27M-mutated diffuse midline #gliomas are universally lethal central nervous system tumors in children and young adults,” observed Sneha Ramakrishna, MD. GD2-targeting chimeric antigen receptor (CAR)-T cells have evidence of benefit for patients. https://t.co/WITpzDblmy https://t.co/RMxc45uDQl