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Mashup Score: 2Elucidating the genetic architecture of DNA methylation to identify promising molecular mechanisms of disease - Scientific Reports - 1 year(s) ago
DNA methylation commonly occurs at cytosine-phosphate-guanine sites (CpGs) that can serve as biomarkers for many diseases. We analyzed whole genome sequencing data to identify DNA methylation quantitative trait loci (mQTLs) in 4126 Framingham Heart Study participants. Our mQTL mapping identified 94,362,817 cis-mQTLvariant-CpG pairs (for 210,156 unique autosomal CpGs) at P < 1e−7 and 33,572,145...
Source: NatureCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 0
Background: Microvascular damage from large artery stiffness (LAS) in pancreatic, hepatic, and skeletal muscles may affect glucose homeostasis. Our goal was to evaluate the association between LAS an
Source: Circulation ResearchCategories: Cardiologists, Latest HeadlinesTweet-
Arterial Stiffness and #Diabetes Risk in #Framingham Heart Study and UK Biobank LA stiffness is associated with increased risk of developing DM #LAS may play an important role in glucose homeostasis and may serve as a useful marker of future DM risk https://t.co/kYVOmVWxjp https://t.co/ILrfqoLIEZ
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Mashup Score: 1Join our Cloud HD Video Meeting - 4 year(s) ago
Zoom is the leader in modern enterprise video communications, with an easy, reliable cloud platform for video and audio conferencing, chat, and webinars across mobile, desktop, and room systems. Zoom Rooms is the original software-based conference room solution used around the world in board, conference, huddle, and training rooms, as well as executive offices and classrooms. Founded in 2011,…
Source: Zoom VideoCategories: Cardiologists, Latest HeadlinesTweet-
Words of wisdom for Salim Yusuf @McMasterU: "#Soweto is not #Framingham" Context is important in #globalhealth research. #Global #Local #RiskFactors Join the meeting at: https://t.co/9w0JUe5Oxk #GlobalHealth #capacity #implementation #ImpSci @NIH @gacd_media #NHLBI @Fogarty_NIH https://t.co/TXEiBnKiM8
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Mashup Score: 0
Objectives This study aimed to assess the performance of carotid ultrasound (US) parameters alone or in combination with Framingham Risk Score (FRS) in discriminating patients with psoriatic arthritis (PsA) with and without coronary artery disease (CAD). Methods Ninety-one patients with PsA (56 males; age: 50±11 years, disease duration: 9.4±9.2 years) without overt cardiovascular (CV) diseases…
Source: RMD OpenCategories: Latest Headlines, RheumatologyTweet-
Further insights for better risk determination for #coronary artery disease in people with #psoriatic arthritis. Combination of carotis intima media thickness and #Framingham risk as valubale tools. https://t.co/WFEjoXGMcs https://t.co/rovmrBDPJh
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Mashup Score: 2Effect of a Comprehensive Cardiovascular Risk Reduction Intervention in Persons With Serious Mental Illness - 4 year(s) ago
This randomized clinical trial examines the effectiveness of an 18-month multifaceted intervention incorporating behavioral counseling, care coordination, and care management for overall cardiovascular risk reduction in adults with serious mental illness.
Source: jamanetwork.comCategories: Cardiologists, Latest HeadlinesTweet-
.@NIH_NHLBI #RCT #JAMA: Delivering a tailored #cardiovascular risk reduction program among #community #MentalHealth outpatients with serious #mentalillness (#schizophrenia #bipolar #depression, etc) significantly reduces #Framingham CVD #risk scores. @NIH https://t.co/0aMjR4hoEP https://t.co/W7QnfgnffB
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Mashup Score: 0
Background: Heart failure (HF) may arise from alterations in metabolic, structural, and signaling pathways, but its genetic architecture is incompletely understood. To elucidate potential genetic c…
Source: www.ahajournals.orgCategories: CardiologistsTweet-
.@NIH_NHLBI-supported #Framingham Heart Study publishes proof-of-concept and hypothesis-generating study that used an integrated multi-omics approach to identify #genetic underpinnings of #HeartFailure and its #echocardiographic precursors. Top 10 #genes. https://t.co/zqRyrwsM5T https://t.co/NuWVYxt7ja
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.@NIH_NHLBI-funded: Jiantao Ma, Dan Levy et al. report putatively causal associations between #DNA methylation biomarkers and #cardiovascular risk factors LDL #cholesterol, #coronary artery disease, and also #COVID19 severity. #Framingham. Read in #Nature https://t.co/SBay6tsusb https://t.co/ww6A23EdNP