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Mashup Score: 4
The introduction of rapid exome sequencing (rES) for critically ill neonates admitted to the neonatal intensive care unit has made it possible to impact clinical decision-making. Unbiased prospective studies to quantify the impact of rES over routine genetic testing are, however, scarce. We performed a clinical utility study to compare rES to conventional genetic diagnostic workup for critically…
Source: SpringerLinkCategories: Latest Headlines, PediatricsTweet
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Mashup Score: 4Current pain management practices for preterm infants with necrotizing enterocolitis: a European survey - Pediatric Research - 1 year(s) ago
Necrotizing enterocolitis (NEC) is a highly painful intestinal complication in preterm infants that requires adequate pain management to prevent short- and long-term effects of neonatal pain. There is a lack of international guidelines for pain management in NEC patients. Therefore, this study aims to describe current pain management for NEC patients in European neonatal intensive care units…
Source: NatureCategories: Latest Headlines, PediatricsTweet-
Lots of variation in how we assess and manage pain for infants with NEC - is it time for a consensus ask ten Barge et al. in a survey of European NICUs in @Ped_Research https://t.co/H4knPN5uwD #neoEBM #EBNEOalerts #neotwitter #FOAMneo https://t.co/1f7jIXPrBJ
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Mashup Score: 0Early prediction of severe retinopathy of prematurity requiring laser treatment using physiological data - Pediatric Research - 1 year(s) ago
Early risk stratification for developing retinopathy of prematurity (ROP) is essential for tailoring screening strategies and preventing abnormal retinal development. This study aims to examine the ability of physiological data during the first postnatal month to distinguish preterm infants with and without ROP requiring laser treatment. In this cohort study, preterm infants with a gestational…
Source: NatureCategories: Latest Headlines, PediatricsTweet-
Machine learning models used by Poppe, @ccroehr @IKMReiss @sinno37222817 et al. in @Ped_Research to predict need for laser therapy for ROP in preterm infants <32 weeks. https://t.co/ODYPWst64z #neoEBM #EBNEOalerts #neotwitter #FOAMneo https://t.co/DxGCF6GaSL
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Mashup Score: 0
Aim: To determine if supplementation of infants born <33 weeks’ gestation with higher dose docosahexaenoic acid (DHA) affects growth, body composition, and blood pressure at 7 y corrected age (CA) and if treatment effects differed by infant sex at birth and birth weight strata (<1250 and ≥1250 g). Methods: Seven-year follow-up of an Australian multicenter randomized controlled trial in which 657...
Source: MDPICategories: Latest Headlines, PediatricsTweet-
Effect of High Maternal or Neonatal DHA on Growth, Body composition and BP at 7-years of age (DINO Trial) published @Nutrients_MDPI by @Karen_P_Best et al https://t.co/ZRCMjpKMVp #neoTwitter #neoEBM #FOAMNeo https://t.co/v73dSZgZBY
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Mashup Score: 0Targeted screening for congenital cytomegalovirus infection: clinical, audiological and neuroimaging findings - 1 year(s) ago
Objective To evaluate clinical, audiological and neuroimaging findings in a cohort of infants diagnosed with congenital cytomegalovirus (cCMV) infection after failure at newborn hearing screening. Methods A prospective observational study in the Netherlands, using the existing newborn hearing screening infrastructure for well babies. Between July 2012 and November 2016, cytomegalovirus (CMV) PCR…
Source: ADC Fetal & Neonatal EditionCategories: Latest Headlines, PediatricsTweet-
Chung et al look at congenital CMV in term infants with failed newborn hearing screening in @ADC_FN https://t.co/stW8p4Oz6s #EBNEOalerts #neoEBM #neotwitter #foamneo https://t.co/3S17zSVVxG
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Mashup Score: 0The publication quality of laboratory values in clinical studies in neonates - Pediatric Research - 1 year(s) ago
There are no generally accepted age-appropriate reference ranges for laboratory values in neonates. This also matters for drug development. The International Neonatal Consortium (INC) is engaged to define actionable reference ranges of commonly used laboratory values in neonates. A structured literature search was performed to identify standards or recommendations for publications that present…
Source: NatureCategories: Latest Headlines, PediatricsTweet-
A post with a difference tonight highlighting an important gap in #neoEBM by @karelallegaert @Hhsuerland in @Ped_Research https://t.co/HLt0g0jBDl #FOAMneo #neotwitter #EBNEOalerts https://t.co/Y9LrNafg6A
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Mashup Score: 2SARS CoV-2 detected in neonatal stool remote from maternal COVID-19 during pregnancy - Pediatric Research - 2 year(s) ago
In utero transmission of SARS coronavirus 2 (SARS-CoV-2) has not been fully investigated. We investigated whether newborns of mothers with COVID-19 during pregnancy might harbor SARS-CoV-2 in the gastrointestinal tract. This cohort study investigated stool from 14 newborns born at 25–41 weeks admitted at delivery to our urban academic hospital whose mothers had COVID-19 during pregnancy. Eleven…
Source: NatureCategories: Latest Headlines, PediatricsTweet-
Could the newborn gut be a reservoir for SARS-CoV-2 if a mother has COVID-19 in pregnancy? Jin et al. share results as part of a retrospective cohort study in @Ped_Research https://t.co/xAUQsJTZkv #EBNEOalerts #neoEBM #neotwitter #FOAMneo https://t.co/C7ClTvPx3m
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Mashup Score: 3
Background The practice of therapeutic hypothermia (TH) is widely used for neonatal hypoxic-ischemic encephalopathy (HIE) despite its corresponding feeding strategies are still controversial. This randomized controlled trial (RCT) demonstrated to evaluate the effect of early vs. delayed enteral nutrition on the incidence of feeding intolerance (FI) and other association during TH. Methods This…
Source: BioMed CentralCategories: Latest Headlines, PediatricsTweet-
A new RCT explores the feasibility and safety of feeding babies with moderate to severe hypoxic-ischemic encephalopathy receiving therapeutic hypothermia https://t.co/wHTgUELGkC #neoEBM #EBNEOAlerts #FOAMNeo https://t.co/8Z4OMIygiw
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Mashup Score: 2Pacifier use and breastfeeding in term and preterm newborns—a systematic review and meta-analysis - European Journal of Pediatrics - 2 year(s) ago
The purpose of this study is to assess whether pacifier use is associated with breastfeeding success in term and preterm newborns and whether it influences hospitalization time in preterm newborns. Four databases were searched for randomized controlled trials (RCTs), and a systematic review and meta-analysis were conducted. The risk of bias and evidence quality, according to the GRADE…
Source: SpringerLinkCategories: Latest Headlines, PediatricsTweet-
A meta-analysis by Tolppola et al @EurJPediatrics suggests that dummy use doesn't negatively affect breastfeeding (term and preterm) and may even reduce time to full oral feeds and length of hospital stay (preterm) https://t.co/h7JnCDygtt #FOAMneo #neoEBM #EBNEOalerts #neotwitter https://t.co/DSJiDCQvHC
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Mashup Score: 0Early-onset neonatal sepsis in the Paris area: a population-based surveillance study from 2019 to 2021 - 2 year(s) ago
Background Early-onset neonatal sepsis (EOS) is a rare condition but an important cause of severe morbidity and mortality in neonates. Methods This is a prospective observational study in neonates born at ≥34 weeks of gestation (WG). The primary endpoint was EOS, defined by isolation of pathogenic species from blood culture and/or cerebrospinal fluid culture within 72 hours after birth. Data on…
Source: ADC Fetal & Neonatal EditionCategories: Latest Headlines, PediatricsTweet-
Contemporaneous Early Onset Sepsis rates in Paris. A game of two halves and much resistance by Sikias et al in @ADC_FN #EBNEOalerts #neoEBM #neotwitter #foamneo https://t.co/fd7HEcng3q https://t.co/cX25Z4RM6u
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Rapid exome sequencing as a first-line method of genetic testing in NICU babies - Olde Keiser, @Willem_Pieter et al. report on behald of the RADICON-NL consortium in @EurJPediatr. https://t.co/fadJVVmQnX #neoEBM #neotwitter #EBNEOalerts #FOAMneo https://t.co/xL2PkLNarm