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Mashup Score: 1Global change in hepatitis C virus prevalence and cascade of care between 2015 and 2020: a modelling study - 1 year(s) ago
At the beginning of 2020, there were an estimated 56·8 million viraemic HCV infections globally. Although this number represents a decrease from 2015, our forecasts suggest we are not currently on track to achieve global elimination targets by 2030. As countries recover from COVID-19, these findings can help refocus efforts aimed at HCV elimination.
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Mashup Score: 7A US plan for HCV elimination - 1 year(s) ago
On Nov 7, 2022, members of the White House Office of Science Technology Policy outlined plans for a US HCV elimination programme at a special session at AASLD’s The Liver Meeting. In a US context, the plan warrants praise for its ambition—many hurdles to successful elimination exist in the country, and progress has been slow and disjointed since the first interferon-free direct-acting antiviral…
Categories: Latest Headlines, PayerTweet
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Mashup Score: 0A US plan for HCV elimination - 1 year(s) ago
On Nov 7, 2022, members of the White House Office of Science Technology Policy outlined plans for a US HCV elimination programme at a special session at AASLD’s The Liver Meeting. In a US context, the plan warrants praise for its ambition—many hurdles to successful elimination exist in the country, and progress has been slow and disjointed since the first interferon-free direct-acting antiviral…
Categories: Gastroenterology, Latest HeadlinesTweet
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Mashup Score: 1
Each year over a quarter of a million children acquire chronic hepatitis B at birth.1 Tens of thousands will go on to lose their lives prematurely from liver cancer or other forms of liver disease.1 These deaths could have been prevented if they had received the hepatitis B birth dose vaccine.
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Mashup Score: 0Patient-centred models of hepatitis C treatment for people who inject drugs: a multicentre, pragmatic randomised trial - 2 year(s) ago
In this trial of active PWID, both models resulted in high SVR. Although adherence was significantly higher in the mDOT group versus the patient navigation group, there was no significant difference in SVR between the groups. Increases in adherence and treatment completion were associated with an increased likelihood of SVR. These results suggest that active PWID can reach high SVRs in diverse…
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Mashup Score: 1New hepatitis B drug development disillusions: time to reset? - 2 year(s) ago
After more than 5 years of intense preclinical and clinical research, the development of new hepatitis B virus (HBV) drugs appears to be stalling. The main reasons for this are the major limitations of the developmental path, including the use of inappropriate endpoints for clinical development, the standards for efficacy and approval being too strict (functional cure after short finite treatment…
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Mashup Score: 0Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 - 2 year(s) ago
The prevalence of chronic HBV infection declined over time, particularly in children younger than 5 years, since the introduction of hepatitis B vaccination. HBV-related death rates also decreased, but HBV-related death counts increased as a result of population growth, ageing, and cohort effects. By 2019, many countries had met the interim seroprevalence target for children younger than 5 years,…
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Mashup Score: 2
Community engagement and advocacy are important to drive development and improvement of service delivery for chronic viral hepatitis. Community engagement is defined as the process of working collaboratively with groups of people affiliated by proximity, interests, or situations to support their wellbeing.1 Appropriate community engagement can help to reduce stigma, disseminate messages, and…
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Mashup Score: 0Nationwide hepatitis C virus screening and treatment of adolescents in Egyptian schools - 2 year(s) ago
Until 2018, Egypt had the highest prevalence of hepatitis C virus (HCV) infection globally, affecting approximately 7% of the population. Despite efforts in diagnosis and treatment since 2006, nearly 2 million individuals with chronic HCV infection had yet to be diagnosed as of early 2018. In December, 2018, a mass HCV screening campaign for adolescents aged 15–18 years was initiated. Among…
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Mashup Score: 0Methods and indicators to validate country reductions in incidence of hepatitis C virus infection to elimination levels set by WHO - 2 year(s) ago
One of the main goals of the 2016 Global Health Sector Strategy on viral hepatitis is the elimination of hepatitis C virus (HCV) as a public health problem by 2030, defined as an 80% reduction in incidence and 65% reduction in mortality relative to 2015. Although monitoring HCV incidence is key to validating HCV elimination, use of the gold-standard method, which involves prospective HCV…
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Data from @PolarisObserv in our May issue helped track progress towards goals for #viralhepatitis elimination, providing global estimates of the change in #HCV prevalence and the cascade of care between 2015 and 2020 https://t.co/ExDW3GEoIS #nohep #endhep #livertwitter https://t.co/v8XnER89Ts