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Mashup Score: 6The role of DNA damage in diabetic complications - 3 month(s) ago
Nature Reviews Endocrinology – Mechanistic and clinical data indicate that DNA damage contributes to the pathogenesis and progression of diabetic complications. Thus, DNA damage and its signalling…
Source: www.nature.comCategories: General Medicine News, EndocrinologyTweet
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Mashup Score: 13Barbados is in the grip of a diabetic foot amputation crisis - 9 month(s) ago
As Barbados faces rising numbers of diabetic foot amputations, the nation’s health experts are mobilising to uncover the root causes that can provide valuable lessons for others. Yemisi Bokinni reports For the past two decades Barbados has held the dubious nickname of “amputation capital of the world,” says Brian Payne, deputy nutrition officer at the Barbados Ministry of Health and Wellness. The reason? A tide of diabetes. A staggering 89% of diabetes related hospital admissions in Barbados involve foot complications.1 Amputations are largely attributed to poorly managed type 2 diabetes, with approximately 80% of cases stemming from diabetic foot ulcers.2 These often develop from diabetes related complications such as diabetic neuropathy and peripheral arterial disease, which contribute to the formation of leg ulcers and delayed wound healing. The gravity of this health crisis is underscored by the stark five year survival rates after amputation in the country: 28% for below knee ampu
Source: www.bmj.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 13Barbados is in the grip of a diabetic foot amputation crisis - 9 month(s) ago
As Barbados faces rising numbers of diabetic foot amputations, the nation’s health experts are mobilising to uncover the root causes that can provide valuable lessons for others. Yemisi Bokinni reports For the past two decades Barbados has held the dubious nickname of “amputation capital of the world,” says Brian Payne, deputy nutrition officer at the Barbados Ministry of Health and Wellness. The reason? A tide of diabetes. A staggering 89% of diabetes related hospital admissions in Barbados involve foot complications.1 Amputations are largely attributed to poorly managed type 2 diabetes, with approximately 80% of cases stemming from diabetic foot ulcers.2 These often develop from diabetes related complications such as diabetic neuropathy and peripheral arterial disease, which contribute to the formation of leg ulcers and delayed wound healing. The gravity of this health crisis is underscored by the stark five year survival rates after amputation in the country: 28% for below knee ampu
Source: www.bmj.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 8
These findings provide evidence that continuous glucose monitoring can reduce severe hypoglycaemia and ketoacidosis risk in young people with type 1 diabetes on insulin therapy. Continuous glucose monitoring metrics might help to identify those at risk for acute diabetes complications.
Source: www.thelancet.comCategories: Endocrinology, Latest HeadlinesTweet
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Mashup Score: 1Anti-vascular endothelial growth factor (anti-VEGF) medicines for diabetic macular oedema - 1 year(s) ago
Diabetic macular oedema is a common complication of diabetes, in which damage to the blood vessels at the back of the eye leads to swelling. Lucentis, Eylea and Avastin are three antiangiogenic drugs that can be injected into the eye to treat these blood vessels and reduce the swelling; and drugs with longer lasting effects have recently become available, such as Vabysmo and Beovue. In June 2023, Katie Curran from Queen’s University Belfast in the UK and colleagues, updated their Cochrane review of these
Source: www.cochrane.orgCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 2Anti-vascular endothelial growth factor (anti-VEGF) medicines for diabetic macular oedema - 1 year(s) ago
Diabetic macular oedema is a common complication of diabetes, in which damage to the blood vessels at the back of the eye leads to swelling. Lucentis, Eylea and Avastin are three antiangiogenic drugs that can be injected into the eye to treat these blood vessels and reduce the swelling; and drugs with longer lasting effects have recently become available, such as Vabysmo and Beovue. In June 2023, Katie Curran from Queen’s University Belfast in the UK and colleagues, updated their Cochrane review of these
Source: www.cochrane.orgCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 0The Sweet Spot - 2 year(s) ago
The links between low blood sugar and diabetic eye disease
Source: The OphthalmologistCategories: Latest Headlines, OphthalmologyTweet
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Mashup Score: 0
These findings provide evidence that continuous glucose monitoring can reduce severe hypoglycaemia and ketoacidosis risk in young people with type 1 diabetes on insulin therapy. Continuous glucose monitoring metrics might help to identify those at risk for acute diabetes complications.
Categories: Endocrinology, Latest HeadlinesTweet
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Mashup Score: 1
These findings provide evidence that continuous glucose monitoring can reduce severe hypoglycaemia and ketoacidosis risk in young people with type 1 diabetes on insulin therapy. Continuous glucose monitoring metrics might help to identify those at risk for acute diabetes complications.
Categories: Endocrinology, Latest HeadlinesTweet
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Mashup Score: 1Answering clinically pertinent questions with real-world data from paediatric type 1 diabetes registries - 2 year(s) ago
The beneficial impact of continuous glucose monitoring (CGM) was shown in adults with type 1 diabetes by the landmark JDRF trial in 2008.1 Yet, for both children and adolescents, limited sensor wear mitigated the ability to detect differences in HbA1c with sensor use.1 However, since that time, trials have shown benefits of sensor therapy in children and adolescents,2 with real world data echoing…
Categories: Endocrinology, Latest HeadlinesTweet
A Comment article from our latest issue: Varun Kumar, Ali Önder Yildirim & Peter Nawroth discuss the role of DNA damage in #diabetic complications (£) https://t.co/xIjaWdQrda https://t.co/vPDUdnEC0f