• Mashup Score: 1
    Evaluating the effects of SARS-CoV-2 Spike mutation D614G on transmissibility and pathogenicity - 3 year(s) ago

    Analysis of the spread and frequency of SARS-CoV-2 D614G in United Kingdom suggests a selective advantage for this strain that is associated with higher viral loads in younger patients but not higher COVID-19 clinical severity or mortality.

    Source: Cell
    Categories: General Medicine News, Latest Headlines
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      CellPressNews

      While there is no association of #SARSCoV2 strain #D614G with greater severity of infection, the #strain is associated with higher viral loads and younger patient age. Read more form this evaluation in @CellCellPress https://t.co/gXvPCZZ5y9 #COVID19 #mutation https://t.co/K7KDOC6QSP

  • Mashup Score: 18
    Making sense of mutation: what D614G means for the COVID-19 pandemic remains unclear - 4 year(s) ago

    Korber et al. (2020) found that a SARS-CoV-2 variant in the spike protein, D614G, rapidly became dominant around the world. While clinical and in vitro data suggest that D614G changes the virus phenotype, the impact of the mutation on transmission, disease, and vaccine and therapeutic development are largely unknown.

    Source: Cell
    Categories: Infectious Disease, Latest Headlines
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      angie_rasmussen

      Out today: commentary from @NathanGrubaugh, @BillHanage, and yours truly on the #SARSCoV2 #D614G variant paper! It's grown up since its preprint days but there's still more to learn about its functional importance for transmission & pathogenesis. https://t.co/YBOXHVB9AE https://t.co/hUg5CwmnFQ

  • Mashup Score: 51
    Tracking changes in SARS-CoV-2 Spike: evidence that D614G increases infectivity of the COVID-19 virus - 4 year(s) ago

    A SARS-CoV-2 variant carrying the Spike protein amino acid change D614G has become the most prevalent form in the global pandemic. Dynamic tracking of variant frequencies revealed a recurrent pattern of G614 increase at multiple geographic levels: national, regional and municipal. The shift occurred even in local epidemics where the original D614 form was well established prior to the…

    Source: Cell
    Categories: General Medicine Journals and Societies, Latest Headlines
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      CellCellPress

      A #SARSCoV2 variant carrying the #Spike #protein amino acid change #D614G is potentially associated with greater #infectivity and higher #viral loads. Online now! https://t.co/bGNsbKQe0B For all @CellPressNews #coronavirus research, visit https://t.co/BCdU2ltXnp #COVID19 https://t.co/puKmnvQNiM