• Mashup Score: 1

    IDSA has developed living, frequently updated evidence-based guidelines to support patients, clinicians and other health-care professionals in their decisions about treatment and management of patients with COVID-19 infection. Summarized here are the recommendations with comments related to the clinical practice guideline for the treatment and management of COVID-19.

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    • ICYMI, #IDSAGuidelines now recommend AGAINST routine use of #convalescentplasma among immunocompetent patients & suggests against use among #immunocompromised patients hospitalized with COVID-19. https://t.co/XdWcNHa1m7 https://t.co/TAqM8KQoKa

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    The New England Journal of Medicine (NEJM) today published final results of a nationwide multicenter study led by researchers at Johns Hopkins Medicine and the Johns Hopkins Bloomberg School of Public Health that show plasma from patients who have recovered from COVID-19 and whose blood contains antibodies against SARS-CoV-2, the causative virus, is an effective and safe option as an early…

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    • Study finds #convalescentplasma can be effective early COVID-19 therapy @nejm https://t.co/jrYf2y6KKC

  • Mashup Score: 23

    IDSA has developed living, frequently updated evidence-based guidelines to support patients, clinicians and other health-care professionals in their decisions about treatment and management of patients with COVID-19 infection. Summarized here are the recommendations with comments related to the clinical practice guideline for the treatment and management of COVID-19.

    Tweet Tweets with this article
    • For evidence appraisal & rationale, please visit https://t.co/YRCxtdzoZT.

    • Update Alert: Revised recommendation on the use of #convalescentplasma in ambulatory patients w/ COVID-19 at high risk of progression to severe disease w/ no other treatment options. 📄: https://t.co/YRCxtdilXT #COVID19Guidelines @JGPharmD @adarsh_bhimraj @RMKGandhi @ShohamTxID https://t.co/KpXnywH362

  • Mashup Score: 21
    Plasma Donation - 2 year(s) ago

    Make your blood donation go further by donating blood plasma. A single AB Elite donation can provide up to three units of plasma to patients in need, giving you the power to make an even greater impact.

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    • If you have had #COVID19, esp if #vaxxed, & you are out of isolation, please donate #convalescentplasma. It can help ppl w/ #Omicron who are #immunocompromised or #immunosuppressed. If not, give 🩸. Supply critically low. #GetVaxxed #GetBoosted #MedTwitter https://t.co/QGaF9JhGBT

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    BACKGROUND The efficacy of polyclonal high titer convalescent plasma to prevent serious complications of COVID-19 in outpatients with recent onset of illness is uncertain. METHODS This multicenter, double-blind randomized controlled trial compared the efficacy and safety of SARS-CoV-2 high titer convalescent plasma to placebo control plasma in symptomatic adults ≥18 years positive for SARS-CoV-2…

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    • 📣#Preprint #COVID19 #ConvalescentPlasma 📌RCT (N=1.2K) 📌Outpatients age 18+ 📌High-titer CCP (>1:320) vs placebo plasma w/in 9d of symptoms 📌Primary endpt: Hosp/death by d28 📌CCP 🏆: 54% ⬇️, driven by non-ICU hospitalizations (NNT=29); HR 0.46, p<.01 https://t.co/bcGwLFf2CL https://t.co/3LEa8ogeGw

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    Convalescent plasma failed to reduce progression to severe respiratory failure or death within 30 days in patients with moderate to severe COVID-19 pneumonia, according to a new study published in JAMA Network Open.“Randomized clinical trials already published or available as preprint versions have not shown a clear benefit of [convalescent plasma] in reducing the risk of disease

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    • In the TSUNAMI trial, #convalescentplasma failed to reduce progression to respiratory failure or death at 30 days in patients with #COVID19 #pneumonia @JAMANetworkOpen @InfectDisNews https://t.co/lnmPA68PVk

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    Results from the CONTAIN COVID-19 trial showed that convalescent plasma did not meet prespecified efficacy endpoints in patients hospitalized with COVID-19. However, exploratory subgroup analyses of the trial revealed that high-titer COVID-19 convalescent plasma (CCP) may have benefited patients before remdesivir and corticosteroids were available, indicating “a heterogenous treatment

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    • #Convalescentplasma may have benefited patients in early days of #COVID19pandemic, researchers wrote https://t.co/Zxq5hSYkl3