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Mashup Score: 0Harnessing the Vnn1 pantetheinase pathway boosts short chain fatty acids production and mucosal protection in colitis - 11 month(s) ago
Objective In the management of patients with IBD, there is a need to identify prognostic markers and druggable biological pathways to improve mucosal repair and probe the efficacy of tumour necrosis factor alpha biologics. Vnn1 is a pantetheinase that degrades pantetheine to pantothenate (vitamin B5, a precursor of coenzyme A (CoA) biosynthesis) and cysteamine. Vnn1 is overexpressed by inflamed…
Source: GutCategories: Gastroenterology, Latest HeadlinesTweet
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Mashup Score: 0Harnessing the Vnn1 pantetheinase pathway boosts short chain fatty acids production and mucosal protection in colitis - 11 month(s) ago
Objective In the management of patients with IBD, there is a need to identify prognostic markers and druggable biological pathways to improve mucosal repair and probe the efficacy of tumour necrosis factor alpha biologics. Vnn1 is a pantetheinase that degrades pantetheine to pantothenate (vitamin B5, a precursor of coenzyme A (CoA) biosynthesis) and cysteamine. Vnn1 is overexpressed by inflamed…
Source: GutCategories: Gastroenterology, Latest HeadlinesTweet
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Mashup Score: 2Harnessing the Vnn1 pantetheinase pathway boosts short chain fatty acids production and mucosal protection in colitis - 11 month(s) ago
Objective In the management of patients with IBD, there is a need to identify prognostic markers and druggable biological pathways to improve mucosal repair and probe the efficacy of tumour necrosis factor alpha biologics. Vnn1 is a pantetheinase that degrades pantetheine to pantothenate (vitamin B5, a precursor of coenzyme A (CoA) biosynthesis) and cysteamine. Vnn1 is overexpressed by inflamed…
Source: GutCategories: Gastroenterology, Latest HeadlinesTweet
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Mashup Score: 0Harnessing the Vnn1 pantetheinase pathway boosts short chain fatty acids production and mucosal protection in colitis - 11 month(s) ago
Objective In the management of patients with IBD, there is a need to identify prognostic markers and druggable biological pathways to improve mucosal repair and probe the efficacy of tumour necrosis factor alpha biologics. Vnn1 is a pantetheinase that degrades pantetheine to pantothenate (vitamin B5, a precursor of coenzyme A (CoA) biosynthesis) and cysteamine. Vnn1 is overexpressed by inflamed…
Source: GutCategories: Gastroenterology, Latest HeadlinesTweet
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Mashup Score: 0Wolters Kluwer Health - 12 month(s) ago
JavaScript Error JavaScript has been disabled on your browser. You must enable it to continue. Here’s how to enable JavaScript in the following browsers: Internet Explorer From the Tools menu, select Options Click the Content tab Select Enable JavaScript Firefox From the Tools…
Source: lww.comCategories: Emergency Medicine, Latest HeadlinesTweet
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Mashup Score: 2Wolters Kluwer Health - 1 year(s) ago
JavaScript Error JavaScript has been disabled on your browser. You must enable it to continue. Here’s how to enable JavaScript in the following browsers: Internet Explorer From the Tools menu, select Options Click the Content tab Select Enable JavaScript Firefox From the Tools…
Source: lww.comCategories: Emergency Medicine, Latest HeadlinesTweet
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Mashup Score: 0
Colorectal cancer is a leading cause of cancer death, and a major risk factor is chronic inflammation. Despite the link between colitis and cancer, the mechanism by which inflammation leads to colorectal cancer is not well understood.
Source: GastroenterologyCategories: Gastroenterology, Latest HeadlinesTweet
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Mashup Score: 1Development and Validation of the TUMMY-UC: A Patient-Reported Outcome for Pediatric Ulcerative Colitis - 1 year(s) ago
The TUMMY-UC is a patient-reported outcome measure for pediatric ulcerative colitis (UC) with an observer-reported outcome version for children aged <8 years. It includes eight items selected by concept elicitation interviews. We aimed to finalize the TUMMY-UC by cognitive interviews (stage 2) and to evaluate the index for its psychometric properties (stage 3).
Source: GastroenterologyCategories: Gastroenterology, Latest HeadlinesTweet
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Mashup Score: 1Anti-Integrin αvβ6 Autoantibodies Are a Novel Biomarker That Antedate Ulcerative Colitis - 1 year(s) ago
Better biomarkers for prediction of ulcerative colitis (UC) development and prognostication are needed. Anti-integrin αvβ6 (anti-αvβ6) autoantibodies have been described in patients with UC. We tested for the presence of anti-αvβ6 antibodies in the preclinical phase of UC and studied their association with disease-related outcomes after diagnosis.
Source: GastroenterologyCategories: Gastroenterology, Latest HeadlinesTweet
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Mashup Score: 2
Join us for an interactive conversation about the Role of Biomarkers for the Management of Ulcerative Colitis. This Gastro Bites session will highlight: -Biomarker-based monitoring strategies in patients with ulcerative colitis. – How to interpret results of common biomarkers of inflammation in patients with UC, in the context of symptoms. – The settings in which biomarkers may be used to replace…
Source: ZoomCategories: Gastroenterology, Latest HeadlinesTweet
#GUTImage from the paper "Harnessing the Vnn1 pantetheinase pathway boosts short chain fatty acids production and mucosal protection in colitis" via https://t.co/CI4hhv6pW6 #Colitis #SCFA @achillebro https://t.co/1XJg6a7XLd