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ScienceDirect

Beyond CD19 CAR-T cells in lymphoma - 5 days

Mashup Score:26

Adoptive transfer of CD19-specific chimeric antigen receptor T-cells (CAR-T cells) has transformed the treatment paradigm of relapsed/refractory...

Key Points. Optimal fludarabine exposure in patients with R/R B-cell ALL undergoing CD19-specific CAR T-cell therapy was AUC ≥ 13.8mg*hr/LSuboptimal...

DNMT3A deletion preserves CAR T cell functionality during prolonged...

Key Points. Treatment with CD19 CART for R/R EM disease, particularly CNS, offers a beneficial option with similar toxicity and survival to BM diseaseThere...

Engineering Novel CD19/CD22 Dual-Target CAR-T Cells for Improved Anti-Tumor Activity. Cancer Investigation. Accepted 8 November...

Chimeric antigen receptor (CAR) T-cell therapy has yielded impressive outcomes and transformed treatment algorithms for hematological malignancies. To date, five CAR T-cell products have...

T cells engineered to express transgenes such as chimeric antigen receptors (CAR) or modified T cell receptors (TCR) represent a new pillar of cancer...

Twenty patients with relapsed B-ALL after HSCT were treated with CAR T cell therapy and were evaluated for efficacy and safety. Twelve patients previously...

Progressive Multifocal Leukoencephalopathy After Chimeric Antigen Receptor T-Cell Therapy for Recurrent Non-Hodgkin...

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lww.com

Wolters Kluwer Health - 6 days

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