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    Reducing metabolic stress within the tumor microenvironment (TME) could be essential for improving the efficacy of cancer immunotherapy. Using a mouse model of melanoma, we show here that appropriately timed treatment with the PPARa agonist fenofibrate improves the ability of a T cell-inducing cancer vaccine to delay tumor progression. Fenofibrate reduced the use of glucose by tumor and stromal…

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    • Manipulating cancer cell and tumor-infiltrating lymphocyte metabolism with PPARα agonist #fenofibrate enhances #CancerVaccine efficacy in melanoma. https://t.co/Pe8xJdxwiN https://t.co/3a5WwzOium

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    New research reveals promising results for a new personalized vaccine for multiple cancer types, including bladder cancer.

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    • Personalized Vaccine Targets Bladder Cancer New research from @MountSinaiNYC shows promise for a new personalized vaccine for multiple cancer types, including #bladdercancer. See how this new treatment could help you: https://t.co/9PX1dbwZQm #cancervaccine #cancerresearch https://t.co/Hnb51Em3p3

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    The success of the COVID-19 vaccines based on messenger RNA has led to a surge of interest from investigators, pharmaceutical companies, and investors in similar technology for other diseases, including a number of oncology indications.

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    • #COVID-19 Jumpstarts RNA Cancer Vaccine Field #COVIDvaccine #cancervaccine https://t.co/7igVtgbH8C

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    Jefferson researchers developing a cancer vaccine to prevent recurrences of gastric, pancreatic, esophageal and colon cancers have added a component that would make the vaccine more effective. The change makes the vaccine less prone to being cleared by the immune system before it can generate immunity against the tumor components. The preclinical studies pave the way for a phase II clinical trial…

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    • Small change makes ##cancervaccine more effective in animal tests https://t.co/uWFLcGfwHw