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    Correspondence to: Michael E. Widlansky, MD, MPH, Medical College of Wisconsin, Hub for Collaborative Medicine, A5743, 8701 W. Watertown Plank Rd., Wauwatosa, WI 53226. Email Department of Respiratory Medicine, Sir Run Run Shaw Hospital and Institute of Translational Medicine, Zhejiang University School of Medicine, Hangzhou, China (P.L.). Cancer center, Zhejiang University, Hangzhou, China (P.L.). Mingyu Liang, MB, PhD, Department of Physiology, University of Arizona College of Medicine, Tucson, 1656 E

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    • Widlansky et al developed a plaque sampling approach that was applied to patients with #CAD. Learn about the feasibility of obtaining #transcriptome information from plaques to identify differences between patient populations https://t.co/rGVD4ptPsQ @MichaelWidlans1 https://t.co/ZpayinvRVH

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    The identification of cardiovascular (CV) diseases before their clinical manifestation is supposed to be a very useful tool to better stratify and manage the CV

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    • The identification of cardiovascular diseases before their manifestation is an evolving field. Which future for the research with advanced imaging technology and biomarkers? https://t.co/EyZzyCLuMM @h_hellmut #biomarkers #imaging #CAD #cardiotwitter @ESC_Journals @escardio https://t.co/he2j0REDGw

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    Coronary artery disease (CAD) is highly prevalent in older adults, yet its management remains challenging. Treatment choices are made complex by the frailty burden of older patients, a high prevalence of comorbidities and body composition abnormalities (e.g., sarcopenia), the complexity of coronary anatomy, and the frequent presence of multivessel disease, as well as the coexistence of major ischemic and bleeding risk factors. Recent randomized clinical trials and epidemiological studies have provided new data on optimal management of complex patients with CAD. However, frail older adults are still underrepresented in the literature. This narrative review aims to highlight the importance of assessing frailty as an aid to guide therapeutic decision-making and tailor CAD management to the specific needs of older adults, taking into account age-related pharmacokinetic and pharmacodynamic changes, polypharmacy, and potential drug interactions. We also discuss gaps in the evidence and offer

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    • JCM | Free Full-Text | Management of Coronary Artery Disease in Older Adults: Recent Advances and Gaps in Evidence. #ACS #Frailty #Teamwork #CAD #OMT #bleeding #SSP https://t.co/tWaikQOOhL