• Mashup Score: 21

    Study Was Evaluating the Use of Apixaban in Patients Treated with Mechanical Aortic Valves ATLANTA, Sept. 23, 2022 /PRNewswire/ — Artivion, Inc. (NYSE: AORT), a leading cardiac and vascular surgery company focused on aortic disease, announced today that it has stopped the PROACT Xa clinical trial, a prospective, randomized, trial designed to determine if patients with an On-X mechanical aortic…

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    • The #PROACT Xa trial has been halted prematurely after it was found that #Apixaban carried a greater risk of blood clots leading to stroke when compared with #warfarin in patients with the on-X mechanical #AV https://t.co/Wqbla1Hr6y @mmamas1973 @HeartOTXHeartMD @SchakrabartiEP https://t.co/a2DbWbMbYC

  • Mashup Score: 4

    This retrospective cohort study uses data from fee-for-service Medicare (2009-2017) and from 2 commercial health insurance (2004-2018) databases to compare extended prescription dispenses for apixaban, rivaroxaban, and warfarin after hospitalization for venous thromboembolism.

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    • #Apixaban, c/w #warfarin, beyond 90d was signif assoc w lower rate of hospitalization for recurrent #VTE, but no signif difference in risk of hospitalization for major bleed;no significant differences for comparisons of apixa vs riva and riva vs warfarin. https://t.co/6tQQRqVMyX

  • Mashup Score: 7

    Anticoagulation with rivaroxaban for patients with atrial fibrillation aged 65 years or more was associated with greater risk for major ischemic and hemorrhagic events compared with apixaban, according to data published in JAMA.“Millions of patients with atrial fibrillation, the most common sustained cardiac arrhythmia, take oral anticoagulants to prevent strokes. The most commonly

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    • Anticoagulation with #rivaroxaban for patients with #AFib aged 65 years or more was associated with greater risk for major ischemic and hemorrhagic events compared with #apixaban @JAMA_current @VUmedicine @healioneurology #Cardiotwitter https://t.co/10kZk9HOs8