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Mashup Score: 1Microfluidic Squeezing Enables MHC Class I Antigen Presentation by Diverse Immune Cells to Elicit CD8+ T Cell Responses with Antitumor Activity - 2 year(s) ago
CD8+ T cell responses are the foundation of the recent clinical success of immunotherapy in oncologic indications. Although checkpoint inhibitors have enhanced the activity of existing CD8+ T cell responses, therapeutic approaches to generate Ag-specific CD8+ T cell responses have had limited
Source: The Journal of ImmunologyCategories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 0High-Fat Diet–Induced Obesity Alters Dendritic Cell Homeostasis by Enhancing Mitochondrial Fatty Acid Oxidation - 2 year(s) ago
This article is featured in Top Reads , p.[][1] [1]: /lookup/volpage/209/1
Source: The Journal of ImmunologyCategories: Allergy-Immunology, Latest HeadlinesTweet-
#JI_TopRead from @JCubRuiz @WeillCornell | Prolonged #highfatdiet in mice inhibits #antigenpresentation by splenic #DCs #ReadTheJI #metabolism #immunology https://t.co/rcRLYcPG0X https://t.co/L03AkjXBf6
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Mashup Score: 32ULK1 inhibition overcomes compromised antigen presentation and restores antitumor immunity in LKB1-mutant lung cancer - 3 year(s) ago
Wong and colleagues show that LKB1-deficient lung tumors are sensitive to autophagy inhibition, which can restore impaired antigen presentation and antitumor immune responses, and propose dual targeting of ULK1 and PD-1 for these tumors.
Source: Nature CancerCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
⭐️ONLINE NOW @NatureCancer: "ULK1 inhibition overcomes compromised #AntigenPresentation and restores #AntitumorImmunity in LKB1-mutant lung cancer", a fantastic study by Kwok-Kin Wong and Co Find it here https://t.co/LzGUVybkHm https://t.co/kVNgkWZQyP #Immunotherapy #LungCancer https://t.co/31FejHO6Hd
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Mashup Score: 4Volume 21 Issue 5, May 2021 - 3 year(s) ago
Volume 21 Issue 5, May 2021
Source: www.nature.comCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
Our May issue, out NOW! With Review articles about #autophagy in anti-tumour immunity, #AntigenPresentation in cancer, targeting FAK, and a Perspective on #EMT programmes in #CancerStemCells. Plus, a Worldview on public engagement! 💌 https://t.co/ctuPucrrP5 @NatResCancer https://t.co/Vf1U0kMZGI
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Mashup Score: 1
Proper management of COVID-19 mandates better understanding of disease pathogenesis. Giamarellos-Bourboulis et al. describe two main features preceding severe respiratory failure associated with COVID-19: the first is macrophage activation syndrome; the second is defective antigen-presentation driven by interleukin-6. An IL-6 blocker partially rescues immune dysregulation in vitro and in patients.
Source: Cell Host & MicrobeCategories: General Medicine News, Latest HeadlinesTweet-
Complex Immune Dysregulation in COVID19 patients w/severe respiratory failure. Macrophage activation syndrome&defective #AntigenPresentation driven by IL-6 precede severe respiratory failure in #COVID19. IL-6 blocker partially rescues #immune dysregulation https://t.co/5Gyht9KIda
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Congratulations @J_Immunol #20MostRead Scott M. Loughhead @SQZBiotech | #Microfluidic Squeezing Enables #MHCI #AntigenPresentation by Diverse #ImmuneCells to Elicit #CD8TCell Responses with #Antitumor Activity #ReadtheJI #immunology https://t.co/9OvjaTv8GO https://t.co/dOJYVvoCkN