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Mashup Score: 0Allopurinol Does Not Improve Cardiovascular Outcomes in Ischaemic Heart Disease Patients - 2 year(s) ago
September 1, 2022 — The gout medicine allopurinol has failed to reduce the primary endpoint of nonfatal myocardial infarction, nonfatal stroke or cardiovascular death in patients with ischaemic heart disease, according to late breaking research presented in a Hot Line session today at ESC Congress 2022. Allopurinol is a xanthine oxidase inhibitor that lowers uric acid and is used to treat…
Source: DAICCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 1Allopurinol fails to improve outcomes in ischemic heart disease - 2 year(s) ago
In patients with ischemic heart disease older than 60 years, the anti-inflammatory drug allopurinol did not improve CV outcomes, according to results of the ALL-HEART trial presented at the European Society of Cardiology Congress. Isla Mackenzie, MBChB (Hon), PhD, FRCP Edin, FBPharmacolS, professor of cardiovascular medicine and honorary consultant physician at University of Dundee and
Source: www.healio.comCategories: Cardiology News and Journals, Latest HeadlinesTweet
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Mashup Score: 4
Objectives The Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout (CARES) trial suggested a higher risk of cardiovascular (CV) death from febuxostat than from allopurinol. However, a significant number of patients died after discontinuation of febuxostat or allopurinol. We investigated whether major adverse cardiovascular events (MACE) and CV death were increased because of…
Source: RMD OpenCategories: Latest Headlines, RheumatologyTweet
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Mashup Score: 2Why Do Patients With Gout Not Take Allopurinol? - 2 year(s) ago
Objective. The objectives of this study were to examine the reasons patients give for nonadherence to allopurinol and to examine differences in intentional nonadherence for patients who did and did not achieve serum urate (SU) levels at treatment target. Methods. Sixty-nine men with gout attending rheumatology clinics, all prescribed allopurinol for ≥ 6 months, completed the Intentional…
Source: The Journal of RheumatologyCategories: Latest Headlines, RheumatologyTweet
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Mashup Score: 1Allopurinol use not linked to increased mortality risk in people with gout, CKD - 2 year(s) ago
Individuals with gout and concurrent chronic kidney disease are no more likely to die following allopurinol initiation, dose escalation, or achievement of target serum urate levels than those not taking the drug, study findings indicate.
Source: rheumatology.medicinematters.comCategories: Latest Headlines, RheumatologyTweet
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Mashup Score: 1Annals of Internal Medicine - 2 year(s) ago
Original ResearchReviewsClinical GuidelinesEditorialsLettersRace/Ethnicity Trends Among U.S. Internal Medicine Residency Applicants and Matriculants: A Cross-Sectional StudyWeb ExclusivesOriginal ResearchReviewsClinical GuidelinesHistory of MedicineEditorialsOn Being a PatientWeb ExclusivesOriginal ResearchEditorialsLettersAntibody Response to a Fourth Messenger RNA COVID-19…
Source: Annals of Internal MedicineCategories: General Medicine Journals and Societies, Latest HeadlinesTweet
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Mashup Score: 0‘Treat-to-target is key’: Allopurinol noninferior to febuxostat for gout when properly dosed - 2 year(s) ago
Allopurinol is noninferior to febuxostat for gout when dosed appropriately as part of a treat-to-target strategy, according to data presented at ACR Convergence 2021.The data emphasize the significance of following the American College of Rheumatology or EULAR treatment recommendations, as opposed to guidelines from the American College of Physicians, which “does not recognize” the
Source: www.healio.comCategories: Latest Headlines, RheumatologyTweet
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Mashup Score: 5‘Treat-to-target is key’: Allopurinol noninferior to febuxostat for gout when properly dosed - 2 year(s) ago
Allopurinol is noninferior to febuxostat for gout when dosed appropriately as part of a treat-to-target strategy, according to data presented at ACR Convergence 2021.The data emphasize the significance of following the American College of Rheumatology or EULAR treatment recommendations, as opposed to guidelines from the American College of Physicians, which “does not recognize” the
Source: www.healio.comCategories: Latest Headlines, RheumatologyTweet
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Mashup Score: 20Cardiovascular risk associated with allopurinol vs. benzbromarone in patients with gout - 3 year(s) ago
AbstractAims . With the high prevalence of gout and associated cardiovascular (CV) diseases, information on the comparative CV safety of individual urate-loweri
Source: OUP AcademicCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 0'Influx of newer agents' in gout pipeline hold promise for shifting treatment paradigm - 3 year(s) ago
Although allopurinol, febuxostat and pegloticase are still relied on to do the heavy lifting in lowering urate for patients with gout, an “influx of newer agents” may help expand effective disease management, according to a presenter here.“In the 21st century, we often think that RA is the most common condition — why? Because we have so many different medications available
Source: www.healio.comCategories: Latest Headlines, RheumatologyTweet
@DAICeditor @escardio #Gout medicine #allopurinol failed to reduce the primary endpoint of nonfatal #myocardialinfarction, nonfatal #stroke or #cardiovasculardeath in patients with #ischaemic #heartdisease, according to #ESCCongress: https://t.co/V9Sz8ET1Tz #esc2022