• Mashup Score: 19
    Mechanisms of ageing: growth hormone, dietary restriction, and metformin - 9 month(s) ago

    Tackling the mechanisms underlying ageing is desirable to help to extend the duration and improve the quality of life. Life extension has been achieved in animal models by suppressing the growth hormone–insulin-like growth factor 1 (IGF-1) axis and also via dietary restriction. Metformin has become the focus of increased interest as a possible anti-ageing drug. There is some overlap in the postulated mechanisms of how these three approaches could produce anti-ageing effects, with convergence on common downstream pathways.

    Source: www.thelancet.com
    Categories: Endocrinology, Latest Headlines
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      TheLancetEndo

      Mechanisms of #ageing: growth hormone, dietary restriction, and #metformin https://t.co/v3xVZPAzxy #aging #antiaging https://t.co/gkrd4cwyJo

  • Mashup Score: 2
    AGING MEDICINE - 9 month(s) ago

    Aging Medicine is an open access journal for international collaboration in multiple research disciplines across the aging sciences.

    Source: onlinelibrary.wiley.com
    Categories: General Medicine Journals and Societies, Latest Headlines
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      Wiley_Health

      ✍️ Call for Papers! Submit your work to the #Aging Medicine special issue: #Cancer in the Elderly. 📅 Submission deadline: December 31, 2023 Get the details now: https://t.co/G2k2XgEQvu #AgingSciences #OpenAccess https://t.co/qxEwZWmIAf

  • Mashup Score: 5
    8 Clues to Living Lover 20 Healthy Years Extra - 9 month(s) ago

    Article courtesy of Dr. Joel Kahn, MD, who is a Clinical Professor of Medicine at Wayne State University School of Medicine, one of the world’s top cardiologists, a best-selling author, lecturer, and a leading expert in plant-based nutrition and holistic care.

    Source: worldhealth.net
    Categories: Latest Headlines, Partners & KOLs
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      drjkahn

      RT @WorldHealth_Net: https://t.co/yuBtT12xDW with @drjkahn #aging #antiaging #longevity #lifespan #lifestyle #diet #exercise #PhysicalActiv…

  • Mashup Score: 1
    The Paradoxical Decline of Geriatric Medicine as a Profession - 9 month(s) ago

    In this Viewpoint, author Jerry Gurwitz discusses the attrition of geriatric medicine as a profession, attributing it in part to societal attitudes about aging and compounded by the negative effects of lower compensation and lack of career prestige.

    Source: jamanetwork.com
    Categories: Healthcare Professionals, Latest Headlines
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      westr

      In this Viewpoint, author Jerry Gurwitz discusses the attrition of #geriatricmedicine as a profession, attributing it in part to societal attitudes about #aging and compounded by the negative effects of lower compensation and lack of career prestige. https://t.co/8Cq5KTsRBk… https://t.co/v2BoQyCYZh

  • Mashup Score: 3
    Association of APOE ε4 Status With Long-term Declines in Odor Sensitivity, Odor Identification, and Cognition in Older US Adults - 9 month(s) ago

    Background and Objectives: The APOE ε4 allele confers susceptibility to faster decline in odor identification and subsequently to Alzheimer’s Disease (AD). Odor identification requires recognizing and naming odors as well as detecting them (odor sensitivity). Whether APOE ε4 is associated with decline of odor sensitivity and whether such decline serves as a harbinger of cognitive decline and AD remains unclear. We determined if and when APOE ε4 affects decline in odor sensitivity, odor identification, and cognition in the National Social Life Health and Aging Project (NSHAP). Methods: We utilized data from NSHAP, a nationally representative survey study of home-dwelling US older adults. Olfaction was measured over time (odor identification in 2005, 2010, and 2015; odor sensitivity in 2010 and 2015; both using validated tests). Cognition was measured with a modified version of the Montreal Cognitive Assessment in 2010 and 2015. Genotyping was performed using DNA samples collected in 201

    Source: n.neurology.org
    Categories: Latest Headlines, Neurology
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      NeurologyToday

      Via @GreenJournal: Testing patients’ odor sensitivity may help predict whether they will experience a decline in cognitive function: https://t.co/NvaD3RiTYV #NeuroTwitter #aging #dementia #Alzheimers @AANMember https://t.co/YGvhZAXi5l

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