• Mashup Score: 22
    News Details - 1 year(s) ago

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    • 3500 patient Flow Trial of #Semaglutide in diabetics with kidney disease stopped early due to effectiveness of drug in preventing progression of kidney disease. #annusmirabilis continues https://t.co/CwGbgHka3q

  • Mashup Score: 0
    News Details - 1 year(s) ago

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    • Unstoppable #GLP1RA semaglutide ‼️ #FLOW, the kidney outcomes trial of once-weekly injectable semaglutide, has stopped early for overwhelming efficacy based on interim analysis. More protection for our patients. https://t.co/qGtV75oaxZ https://t.co/d6mFOIwnwf

  • Mashup Score: 4
    News Details - 1 year(s) ago

    Novo Nordisk will stop the once-weekly injectable semaglutide kidney outcomes trial, FLOW, based on interim analysis Bagsværd, Denmark, 10 October 2023 – Novo Nordisk today announced the decision to stop the kidney outcomes trial FLOW (Effect of semaglutide versus placebo on the progression of renal impairment in people with type 2 diabetes and chronic kidney disease). The decision to stop the trial is based on a recommendation from the independent Data Monitoring Committee (DMC) concluding that the

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    • After CREDENCE, DAPA-CKD, & EMPA-KIDNEY, FLOW is 4th RCT in CKD to be stopped early. All 4 RCTs are event-driven; 3 were stopped at 50-60% accrual of planned events. How many of planned 854 events accrued in FLOW? Last time a HF RCT was stopped early? https://t.co/poTq0xN8Lb

    • Kidney outcomes trial of the GLP-1RA semaglutide 💉in patients w/ T2D + CKD (FLOW) stopped early for efficacy https://t.co/Cp9qSax66Y https://t.co/3LncTHJRI7

  • Mashup Score: 144
    News Details - 1 year(s) ago

    Novo Nordisk will stop the once-weekly injectable semaglutide kidney outcomes trial, FLOW, based on interim analysis Bagsværd, Denmark, 10 October 2023 – Novo Nordisk today announced the decision to stop the kidney outcomes trial FLOW (Effect of semaglutide versus placebo on the progression of renal impairment in people with type 2 diabetes and chronic kidney disease). The decision to stop the trial is based on a recommendation from the independent Data Monitoring Committee (DMC) concluding that the

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    • 2023, the year the #GLP1RA semaglutide can’t lose! #FLOW, the kidney outcomes trial of once-weekly injectable semaglutide, has stopped early for overwhelming efficacy based on interim analysis Massive news, results in Q1 2024 https://t.co/NIwf8km7Oy https://t.co/deCTcdbxpe

    • A remarkable transformation of care for people with diabetes and kidney disease in less than a decade. Before? Limited to only to RAS blockade. Now? Combination therapy with: - RASi - SGLT2i - GLP-1 RA - ns-MRA 4 pillars of care for diabetes & CKD https://t.co/zHoEs9vx4E https://t.co/kFkcHHcUoy

  • Mashup Score: 9
    News Details - 1 year(s) ago

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    • SELECT trial: Among 17k w overweight/obesity (BMI >27) & CVD but w/o diabetes, semaglutide 2.4mg sc v placebo led to 20% reduction in MACE https://t.co/yiQRvpxv3W @novonordisk

  • Mashup Score: 125
    News Details - 1 year(s) ago

    Bagsværd, Denmark, 8 August 2023 – Novo Nordisk today announced the headline results from the SELECT cardiovascular outcomes trial. The double-blinded trial compared subcutaneous once-weekly semaglutide 2.4 mg with placebo as an adjunct to standard of care for prevention of major adverse cardiovascular events (MACEs) over a period of up to five years. The trial enrolled 17,604 adults aged 45 years or older with overweight or obesity and established cardiovascular disease (CVD) with no prior history of

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    • Major Breaking News: A once weekly injection of of obesity drug #Semaglutide reduces the risk of major adverse cardiovascular events by 20% in adults who are overweight or obese in the SELECT trial https://t.co/s4c7W8B5Qn

    • HUGE result! SELECT RCT of semaglutide reduces composite of heart attack, stroke, & cardiovascular death in patients w/o diabetes but w/ history of CVD & overwt/obesity Need to see full report, but likely this will be std secondary prevention tx https://t.co/xQ8v4kMPQ8 https://t.co/aa5z3P0loR

    • the SELECT randomised trial of Ozempic/semaglutide v placebo reduced Heart attacks/strokes/CV death by 20% in non diabetic adults with higher BMI & established cardiovascular disease (CVD) we may be giving all overweight CAD patients GLP1s @PCCS_UK https://t.co/byfED5AC8W

  • Mashup Score: 4

    Our Changing Diabetes in Children programme (CDiC) is changing the future for children with type 1 diabetes in low and middle income countries.

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    • #ISPAD is happy to have been part of the #ChangingDiabetesInChildren #Hackathon this past weekend, hacking #DigitalHealth innovations for #Type1Diabetes. More details to come and visit https://t.co/l1PypEW10Y to learn more! @NovoNordisk @Roche @HarvardChanSPH @mithackmed https://t.co/3vL5eeZCKf

  • Mashup Score: 0

    Our Changing Diabetes in Children programme (CDiC) is changing the future for children with type 1 diabetes in low and middle income countries.

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    • #Type1Diabetes requires a high level of patient knowledge. Together with #ChangingDiabetesinChildren, we’ve developed patient education materials to support children and youth like Matthewos. The materials are available in 5 languages for download here: https://t.co/3he3TaefBp https://t.co/6s2q2J3xPG