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Mashup Score: 34
The OPTION trial of Watchman after ablation for AF vs anticoagulation was positive. John Mandrola questions the conclusions and fears the rise in percutaneous left atrial appendage closure procedures.
Source: www.medscape.comCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 9FDA Plans to Ban Popular Cold Med - 20 day(s) ago
Data review shows that oral phenylephrine is not effective as a decongestant, agency says
Source: www.medpagetoday.comCategories: General Medicine News, CardiologistsTweet-
Oral phenylephrine decongestant will likely be removed from market by FDA due to lack of efficacy https://t.co/z5tJrnfbNe
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Mashup Score: 6CMS Adjusts Nuclear Medicine Reimbursement Policy, Expanding Access to Life-Saving Scans - 23 day(s) ago
The Society of Nuclear Medicine and Molecular Imaging (SNMMI) is celebrating a landmark victory for patients and care providers as the Centers for Medicare & Medicaid Services (CMS) announced a significant adjustment…
Source: snmmi.orgCategories: General Medicine News, CardiologistsTweet-
CMS will allow high cost radiotracers to be separately reimbursed in hospital outpt depts Major implications for patient access to advanced PET scans for dementia, heart disease, cancer, etc. Thanks to extensive advocacy by @SNM_MI https://t.co/9RdShon9x0… https://t.co/drnF4LL1R2
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Mashup Score: 3Downed high-flux reactor could restart sooner than anticipated - 27 day(s) ago
The announcement will come as welcome news, as nuclear medicine departments in numerous regions have been grappling with shortages of Mo-99 and Tc-99m.
Source: healthimaging.comCategories: General Medicine News, CardiologistsTweet-
Great news about the Mo99/Tc99 supply chain! Looks like two currently down reactors (HFR and MARIA) may restart in the next few days. If so, this could mean nuclear cardiology/medicine services will be back to normal soon-ish. https://t.co/pZVa6a1X7P
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Mashup Score: 1Radioactive Decay | Circulation - 1 month(s) ago
In the United States, single-photon emission computed tomography myocardial perfusion imaging (SPECT MPI) accounts for the overwhelming majority of noninvasive imaging procedures for stable ischemic heart disease. 1 Most contemporary SPECT MPI is performed using blood-flow radiotracers labeled with technetium-99m (Tc-99m), which have supplanted thallium-201, an older radiotracer. Tc-99m offers several advantages including superior image quality, lower radiation exposure, and higher overall diagnostic
Source: www.ahajournals.orgCategories: General Medicine News, CardiologistsTweet-
Commentary piece on the (recurrent) problem: https://t.co/x8Np6DOnvT
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Mashup Score: 2Cardiac Stress Testing and the Radiotracer Supply Chain - 1 month(s) ago
This article discusses the clinical effects of a 6-month shortage of technetium Tc 99m, a radiotracer used in cardiac stress testing.
Source: jamanetwork.comCategories: General Medicine News, CardiologistsTweet-
Here is a research article on impact of prior disruption with @bnallamo: https://t.co/29W7uNkcG7
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Mashup Score: 10GitHub - venkmurthy/vmtools - 1 month(s) ago
Contribute to venkmurthy/vmtools development by creating an account on GitHub.
Source: github.comCategories: General Medicine News, CardiologistsTweet-
Ended up making wrapper functions for qsave/qread functions from {qs} which enables saving of multiple files called mqsave/mqread. Find them here: https://t.co/GJPtTmLIKn Install using: devtools::install_github("venkmurthy/vmtools") https://t.co/YNKo681O0r
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Mashup Score: 8
Reduction of LDL cholesterol with simvastatin 20 mg plus ezetimibe 10 mg daily safely reduced the incidence of major atherosclerotic events in a wide range of patients with advanced chronic kidney disease.
Source: www.thelancet.comCategories: General Medicine News, CardiologistsTweet-
@drjohnm What about the SHARP trial? https://t.co/Dumaq0nWFk
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Mashup Score: 55Half-Life and Clearance of Cardiac Troponin I and Troponin T in Humans | Circulation - 2 month(s) ago
BACKGROUND: Cardiac troponin (cTn) is key in diagnosing myocardial infarction (MI). After MI, the clinically observed half-life of cTn has been reported to be 7 to 20 hours, but this estimate reflects the combined elimination and simultaneous release of cTn from cardiomyocytes. More precise timing of myocardial injuries necessitates separation of these 2 components. We used a novel method for determination of isolated cTn elimination kinetics in humans. METHODS: Patients with MI were included within 24 hours after revascularization and underwent plasmapheresis to obtain plasma with a high cTn concentration. After at least 3 weeks, patients returned for an autologous plasma retransfusion followed by blood sampling for 8 hours. cTn was measured with 5 different high-sensitivity cTn assays. RESULTS: Of 25 included patients, 20 participants (mean age, 64.5 years; SD, 8.2 years; 4 women [20%]) received a retransfusion after a median of 5.8 weeks (interquartile range, 5.0–6.9 weeks) after MI
Source: www.ahajournals.orgCategories: General Medicine News, CardiologistsTweet-
Highly innovative experiment in @CircAHA using plasmapheresis shows that the half life of troponin is much shorter than previously thought. This means troponin is released after MI for longer than previously believed. https://t.co/v7TYuEzlvK https://t.co/wEO7rwZY3Q
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Mashup Score: 55Half-Life and Clearance of Cardiac Troponin I and Troponin T in Humans | Circulation - 2 month(s) ago
BACKGROUND: Cardiac troponin (cTn) is key in diagnosing myocardial infarction (MI). After MI, the clinically observed half-life of cTn has been reported to be 7 to 20 hours, but this estimate reflects the combined elimination and simultaneous release of cTn from cardiomyocytes. More precise timing of myocardial injuries necessitates separation of these 2 components. We used a novel method for determination of isolated cTn elimination kinetics in humans. METHODS: Patients with MI were included within 24 hours after revascularization and underwent plasmapheresis to obtain plasma with a high cTn concentration. After at least 3 weeks, patients returned for an autologous plasma retransfusion followed by blood sampling for 8 hours. cTn was measured with 5 different high-sensitivity cTn assays. RESULTS: Of 25 included patients, 20 participants (mean age, 64.5 years; SD, 8.2 years; 4 women [20%]) received a retransfusion after a median of 5.8 weeks (interquartile range, 5.0–6.9 weeks) after MI
Source: www.ahajournals.orgCategories: General Medicine News, CardiologistsTweet-
Highly innovative experiment in @CircAHA using plasmapheresis shows that the half life of troponin is much shorter than previously thought. This means troponin is released after MI for longer than previously believed. https://t.co/v7TYuEzlvK https://t.co/wEO7rwZY3Q
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RCTs are the highest form of medical evidence. That said they can have important weaknesses. @drjohnm discusses his concerns with OPTION trial of left atrial appendage closure versus oral anticoagulation. Worth a read! https://t.co/8gmLCuBKix