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Mashup Score: 31
Primary Myelofibrosis previously also known as Agnogenic Myeloid Metaplasia or Idiopathic Myelofibrosis is a complex myeloproliferative disease. Although the initial genetic insult that causes uncontrolled proliferation of the defective Hematopoietic Stem Cell/Hematopoietic Progenitor Cell is still elusive, literature is being enriched with reports on the molecular mechanisms that provide growth advantage to the mutant clone and the secondary events that lead to stem cell mobilization, bone marrow
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Mashup Score: 1Allergen skin test responses in broad U.S. asthma population in those with and without rhinitis - 5 month(s) ago
Background: Asthma and allergic rhinitis are pathologically interlinked conditions. Despite skin testing (ST) being pivotal for evaluating allergic sensitization, U.S. data that date back to 1960s on ST reactivity patterns in subjects with asthma remain sparse. Objective: The purpose of this study was to elucidate seasonal, perennial ST responses, and their relationship with asthma severity, early versus late onset disease, and immunoglobulin E (IgE) levels. Methods: Five hundred patients with asthma
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Mashup Score: 5Standardization of food allergen ladders for optimal effectiveness and patient safety - 10 month(s) ago
The use of extensively heated (EH) milk and egg products, and dietary advancement therapies such as milk and egg ladders is increasingly common for the management of milk and egg allergies. Although the majority of patients with milk and egg allergies will outgrow their allergies, the ability to tolerate extensively hydrolyzed forms of these allergens is an early indicator of developing long-term tolerance. The denaturation of conformational epitopes during the heating process reduces the allergenicity
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Mashup Score: 22Armand Van Deun â pioneering public health physician (1953â2023) - 10 month(s) ago
N o Reference information available – sign in for access. Affiliations: 1: Tuberculosis Consultant Services, Kirchlindach, Switzerland 2: Formerly Damien Foundation, Brussels, Belgium 3: Institute of Tropical Medicine, Antwerp, Belgium 4: Damien Foundation, Niamey, Niger 5: Public Health Consulting, Joensuu, Finland 6: Laboratoire National de RĂ©fĂ©rence des MycobactĂ©ries, Dakar, SĂ©nĂ©gal 7: Independent Consultant, Paris, France 8: International Union Against Tuberculosis and Lung Disease, Paris, France 9:
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Mashup Score: 3Variability in Cultural Understandings of Consciousness: A Call for Dialogue with Native Psychologies - 1 year(s) ago
Investigation of Indigenous concepts and their meanings is highly inspirational for contemporary science because these concepts represent adaptive solutions in various environmental and social milieus. Past research has shown that conceptualizations of consciousness can vary widely between cultural groups from different geographical regions. The present study explores variability among a few of the thousands of Indigenous cultural understandings of consciousness. Indigenous concepts of consciousness are
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Mashup Score: 1Understanding patient-level costs of weekly isoniazid-rifapentine...: Ingenta Connect - 1 year(s) ago
BACKGROUND: Twelve weeks of weekly isoniazid and rifapentine (3HP) prevents TB disease among people with HIV (PWH), but the costs to people of taking TB preventive treatment is not well described. METHODS: We surveyed PWH who initiated 3HP at a large urban HIV/AIDS clinic in Kampala, Uganda, as part of a larger trial. We estimated the cost of one 3HP visit from the patient perspective, including…
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Mashup Score: 0Comparative efficacy and safety of different hemostatic medicatio...: Ingenta Connect - 2 year(s) ago
Background:Significant blood loss is still one of the most frequent issues in spinal surgery. There were different hemostatic methods to prevent blood loss during spinal surgery. However, the optimal hemostatic therapy for spinal surgery is controversial. The purpose of this study was to assess the efficacy and safety of different hemostatic therapies in spinal surgery. Methods:Two independent…
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Mashup Score: 0Variation in diagnosis and management of allergic reactions among...: Ingenta Connect - 2 year(s) ago
Background:Children with anaphylaxis often emergently present for treatment. Providers’ adherence to the principles of optimal management according to the most recent national guidelines is unknown. Objective:To assess the variation in management approaches for allergic reactions and anaphylaxis between allergy/immunology (AI) and emergency medicine (EM) providers. Methods:This was a…
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Mashup Score: 0Atopic children are more susceptible to viral respiratory infecti...: Ingenta Connect - 2 year(s) ago
Background:The susceptibility of the atopic population to respiratory infections (RI) has not been fully elucidated. This susceptibility is attributed to the immune dysregulation that characterizes atopic diseases. Although, the exact mechanisms involved are not fully understood, there is evidence that shows that the maturation of innate immunity progresses differently in patients with atopy….
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Mashup Score: 3
Objective: In this study, we tested the effect of wearable activity monitors and tracking on physical activity over 2 weeks. Methods: Ninety young adults participated. Prior to initiation of the study, each participant was asked to download an iPhone app that tracked physical activity level (step counts) but were not told the app’s purpose. Each participant was then randomly assigned to one of 3…
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Epigenetic Modifications: New Therapeutic Targets in Primary Myelofibrosis https://t.co/GeQv0iDznK #mpnsm https://t.co/qoJvn5HMYa