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Mashup Score: 19
Individuals with a low estimated glomerular filtration rate (eGFR) are at a high risk of death. Yet, the causes underpinning this association are largely uncertain. This study aimed to assess the causal relationship of low eGFR with all-cause and cause-specific mortality.
Source: www.ajkd.orgCategories: General Medicine News, NephrologyTweet
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Mashup Score: 41A Holistic Framework for the Evaluation of Kidney Function in a Gender-Diverse Landscape - 23 hour(s) ago
The most commonly used equations to estimate glomerular filtration rate incorporate a binary male-female sex coefficient, which has important implications for the care of transgender, gender-diverse, and nonbinary (TGD) people. Whether “sex assigned at birth“ or a binary “gender identity“ is most appropriate for the computation of estimated glomerular filtration rate (eGFR) is unknown. Furthermore, the use of gender-affirming hormone therapy (GAHT) for the development of physical changes to align TGD people with their affirmed gender is increasingly common, and may result in changes in serum creatinine and cystatin C, the biomarkers commonly used to estimate glomerular filtration rate.
Source: www.ajkd.orgCategories: General Medicine News, NephrologyTweet
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Mashup Score: 40
A 17-year-old girl was admitted to the hospital with a 10-day history of bilateral flank pain radiating to the back, associated with low-grade fever without urinary symptoms. She had no significant medical history and denied exposure to any medications in the recent past. Findings on physical examination included an oral temperature of 100°F, pulse rate of 90 beats/min, and blood pressure of 100/70 mm Hg without postural decrease on sitting up. She had conjunctival pallor. The chest and cardiovascular examination had unremarkable findings.
Source: www.ajkd.orgCategories: General Medicine News, NephrologyTweet-
#Quiz A 17-year-old girl was admitted to hospital with 10-day history of bilateral flank pain radiating to the back, associated with low-grade fever without urinary symptoms. She had conjunctival pallor. What does the kidney biopsy show? https://t.co/D4cdBkx5lS (FREE) @draalok https://t.co/d9iHKfb4oZ
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Mashup Score: 142Atypical Anti-Glomerular Basement Membrane Nephritis: A Case Series From the French Nephropathology Group - 2 day(s) ago
Atypical anti-glomerular basement membrane (GBM) nephritis is characterized by a bright linear immunoglobulin staining along the GBM by immunofluorescence without a diffuse crescentic glomerulonephritis nor serum anti-GBM antibodies by conventional ELISA. We characterized a series of patients with atypical anti-GBM disease.
Source: www.ajkd.orgCategories: General Medicine News, NephrologyTweet
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Mashup Score: 5Development and Validation of the Rating of CKD Knowledge Among Older Adults (Know-CKD) with Kidney Failure - 2 day(s) ago
Few older adults with kidney failure engage in shared decision-making (SDM) for kidney replacement therapy. Absence of instruments assessing SDM-relevant knowledge domains may contribute to this. We assessed the reliability and validity of a new instrument, the Rating of CKD Knowledge Older Adults (Know-CKD).
Source: www.ajkd.orgCategories: General Medicine News, NephrologyTweet
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Mashup Score: 3
Chronic kidney disease affects an estimated 37 million people in the United States; of these, >800,000 have end-stage renal disease requiring chronic dialysis or a kidney transplant to survive. Despite efforts to increase the donor kidney supply, approximately 100,000 people are registered on the kidney transplant waitlist with no measurable decrease over the past 2 decades. Outcomes of kidney transplantation are significantly better than for chronic dialysis: kidney transplant recipients have lower rates of mortality and cardiovascular events and better quality of life, but waitlist time matters.
Source: www.ajkd.orgCategories: General Medicine News, NephrologyTweet
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Mashup Score: 14
The prevalence of community-acquired AKI (CA-AKI) in the United States (US) and its clinical consequences are not well described. Our objective was to describe the epidemiology and clinical outcomes associated with CA-AKI.
Source: www.ajkd.orgCategories: General Medicine News, NephrologyTweet
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Mashup Score: 7Referral and Beyond: Restructuring the Kidney Transplant Process to Support Greater Access in the United States - 3 day(s) ago
Advocates for improved equity in kidney transplant in the US have recently focused efforts on initiatives to increase referral for transplant evaluation. However, because donor kidneys remain scarce, increased referrals are likely to result in an increasing number of patients proceeding through the evaluation process without ultimately receiving a kidney. Unfortunately, the process of referral and evaluation can be highly resource-intensive for patients, families, transplant programs, and payers.
Source: www.ajkd.orgCategories: General Medicine News, NephrologyTweet
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Mashup Score: 9How Low Can You Go With Dose of Continuous Kidney Replacement Therapy? Is That the Right Question to Ask? - 4 day(s) ago
Less is more. Illustrations of the validity of this mantra in life and clinical medicine are not hard to find. Examples abound in the realm of critical care, such as with mechanical ventilation1 and transfusion targets.2 Perhaps the best example in critical care nephrology is in dose of continuous kidney replacement therapy (CKRT) for acute kidney injury (AKI). Early enthusiasm for the routine use of high-dose CKRT fueled by smaller single-center studies was halted by the publication in 2008 and 2009 of the VA/NIH Acute Renal Failure Trial Network (ATN) and the Randomized Evaluation of Normal vs Augmented Level (RENAL) Replacement Therapy studies.
Source: www.ajkd.orgCategories: General Medicine News, NephrologyTweet
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Mashup Score: 1
To examine the relationship between neighborhood poverty and deprivation, chronic kidney disease (CKD) comorbidities, and disease progression in children with CKD.
Source: www.ajkd.orgCategories: General Medicine News, NephrologyTweet
Kidney Function Measures and Mortality: A Mendelian Randomization Study https://t.co/k4HE3CUAql #OpenAccess @HaggSara @DorotheaNitsch @GuobinSu @jjcarrero1 #VisualAbstract https://t.co/T7rwf6nrWD