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Mashup Score: 2Genetically proxied lean mass and risk of Alzheimer’s disease: mendelian randomisation study - 10 month(s) ago
Objective To examine whether genetically proxied lean mass is associated with risk of Alzheimer’s disease. Design Mendelian randomisation study. Setting The UK Biobank study and genome wide association study meta-analyses of Alzheimer’s disease and cognitive performance. Participants Summary level genetic data from: 450 243 UK Biobank participants with impedance measures of lean mass and fat…
Source: BMJ MedicineCategories: Latest Headlines, NeurologyTweet
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Mashup Score: 1
Objective To measure the impact of the covid-19 pandemic on admissions to hospital and interventions for acute ischemic stroke and acute myocardial infarction. Design A retrospective analysis. Setting 746 qualifying hospitals in the USA from the Premier Healthcare Database. Participants Patients aged 18 years and older who were admitted to hospital with a primary diagnosis of acute ischemic…
Source: BMJ MedicineCategories: Infectious Disease, Latest HeadlinesTweet
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Mashup Score: 3
Objective To evaluate the impact of conducting all possible pooled analyses across different combinations of randomised controlled trials and endpoints. Design Multiverse analysis, consisting of numerous pooled analyses of individual participant data. Setting Individual patient data from 12 randomised controlled trials comparing canagliflozin treatment with placebo, shared on the Yale…
Source: BMJ MedicineCategories: Hem/Oncs, Latest HeadlinesTweet-
Results from pooled analyses can b subjct 2 vibratn of effects & shud b critically appraised, especially regardng risk 4 selection & availability bias in indiv' participant data retrievd https://t.co/nEC3TJzho8, write @NaudetFlorian @BoussageonR @JoshuaDWallach & @jsross119 et al https://t.co/o81rcZRcl0
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Mashup Score: 3
Objective To implement complex, PINCER (pharmacist led information technology intervention) prescribing indicators, on a national scale with general practice data to describe the impact of the covid-19 pandemic on safe prescribing. Design Population based, retrospective cohort study using federated analytics. Setting Electronic general practice health record data from 56.8 million NHS patients…
Source: BMJ MedicineCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 1Impact of work schedules of senior resident physicians on patient and resident physician safety: nationwide, prospective cohort study - 1 year(s) ago
Objective To determine whether long weekly work hours and shifts of extended duration (≥24 hours) are associated with adverse patient and physician safety outcomes in more senior resident physicians (postgraduate year 2 and above; PGY2+). Design Nationwide, prospective cohort study. Setting United States, conducted over eight academic years (2002-07, 2014-17). Participants 4826 PGY2+ resident…
Source: BMJ MedicineCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 0Impact of work schedules of senior resident physicians on patient and resident physician safety: nationwide, prospective cohort study - 1 year(s) ago
Objective To determine whether long weekly work hours and shifts of extended duration (≥24 hours) are associated with adverse patient and physician safety outcomes in more senior resident physicians (postgraduate year 2 and above; PGY2+). Design Nationwide, prospective cohort study. Setting United States, conducted over eight academic years (2002-07, 2014-17). Participants 4826 PGY2+ resident…
Source: BMJ MedicineCategories: General Medicine Journals and Societies, Latest HeadlinesTweet
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Mashup Score: 3Impact of work schedules of senior resident physicians on patient and resident physician safety: nationwide, prospective cohort study - 1 year(s) ago
Objective To determine whether long weekly work hours and shifts of extended duration (≥24 hours) are associated with adverse patient and physician safety outcomes in more senior resident physicians (postgraduate year 2 and above; PGY2+). Design Nationwide, prospective cohort study. Setting United States, conducted over eight academic years (2002-07, 2014-17). Participants 4826 PGY2+ resident…
Source: BMJ MedicineCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 25Clinical outcomes of myocarditis after SARS-CoV-2 mRNA vaccination in four Nordic countries: population based cohort study - 1 year(s) ago
Objective To investigate the clinical outcomes of myocarditis associated with mRNA vaccines against the SARS-CoV-2 virus compared with other types of myocarditis. Design Population based cohort study. Setting Nationwide register data from four Nordic countries (Denmark, Finland, Norway, and Sweden), from 1 January 2018 to the latest date of follow-up in 2022. Participants The Nordic…
Source: BMJ MedicineCategories: Expert Picks, Latest HeadlinesTweet
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Mashup Score: 0Reproductive outcomes in women and men conceived by assisted reproductive technologies in Norway: prospective registry based study - 1 year(s) ago
Objectives To determine whether the perinatal outcomes of women or men who were conceived by assisted reproductive technologies are different compared with their peers who were naturally conceived. Design Prospective registry based study. Setting Medical Birth Registry of Norway. Participants People born in Norway between 1984 and 2002 with a registered pregnancy by the end of 2021. Exposure…
Source: BMJ MedicineCategories: Healthcare Professionals, Latest HeadlinesTweet
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Mashup Score: 0
Objective To examine sociodemographic inequalities in people with SARS-CoV-2 during the second (alpha) and third (delta) waves of the covid-19 pandemic. Design Retrospective, population based cohort study. Setting Resident population of England. Participants 39 006 194 people aged 10 years and older who were enumerated in the 2011 census, registered with the NHS, and alive on 1 September…
Source: BMJ MedicineCategories: General Medicine Journals and Societies, Latest HeadlinesTweet
“Genetically proxied lean mass and risk of Alzheimer’s disease: mendelian randomisation study” by Iyas Daghlas et al. BMJ Medicine https://t.co/dLVyesChs9 2/2 https://t.co/dtLQr3vLlS