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Mashup Score: 3Infections following bispecific antibodies in myeloma: a systematic review and meta-analysis - 2 hour(s) ago
Abstract. Bispecific antibodies, a novel immunotherapy with promising efficacy against multiple myeloma, form immune synapses between T-cell surface marker CD3
Source: ashpublications.orgCategories: General Medicine News, Partners & KOLsTweet
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Mashup Score: 0LNKing eosinophilia and atherothrombosis - 2 hour(s) ago
In this issue of Blood, Dou et al1 reveal a decisive role for hematopoietic lymphocyte adapter protein (LNK) deficiency in promoting eosinophilia, systemic
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Mashup Score: 0A molecular circuit linking the BCR to the NAD biosynthetic enzyme NAMPT is an actionable target in Richter syndrome - 2 hour(s) ago
BCR cross-linking activates a positive feedback loop including NAMPT and sirtuins and converging on AKT activation.PI3Kγ/δ and NAMPT inhibitors synergize i
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Mashup Score: 1Hypercalcemia in Individuals with Monoclonal Gammopathy of Undetermined Significance: Results from the Istopmm Study - 2 hour(s) ago
Introduction Multiple myeloma (MM) is a malignancy of bone marrow plasma cells, characterized by monoclonal immunoglobulins in the blood or urine and assoc
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Mashup Score: 0
Background: Lenalidomide/dexamethasone has been approved as a standard treatment in multiple myeloma and is applied preferentially in older patients with c
Source: ashpublications.orgCategories: General Medicine News, Partners & KOLsTweet
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Mashup Score: 0
Abstract. Background: Multiple myeloma (MM) patients are immunocompromised due to defects in humoral/cellular immunity and immunosuppressive therapy. Repor
Source: ashpublications.orgCategories: General Medicine News, Hem/OncsTweet-
Suboptimal Humoral and Cellular Immune Response to SARS-CoV-2 RNA Vaccination in Myeloma Patients Is Associated with Anti-CD38 and BCMA-Targeted Treatment [Nov 23, 2021] @ovanoekelen Abstract 882 #ASH21 https://t.co/2tij6MOhju #COVID19Vaccine #COVID19nCancer #mmsm cc @COVID19nCCC https://t.co/pdjQ5Fewq5
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Mashup Score: 0Efficacy of the BNT162b2 mRNA COVID-19 vaccine in patients with chronic lymphocytic leukemia - 2 hour(s) ago
Patients with chronic lymphocytic leukemia (CLL) have been previously shown to have poor responses to antibacterial and antiviral vaccines. In a Plenary Pa
Source: ashpublications.orgCategories: General Medicine News, Hem/OncsTweet-
Efficacy of @BioNTech_Group @pfizer BNT162b2 mRNA #COVIDVaccine in Pts w/ CLL [6/10/21] @herishanu et al @BloodJournal https://t.co/FDK9EzcZ46 #NCT04746092 #COVID19nCancer #CLLsm #leusm #CCC19 #COVID19 @COVID19nCCC Ab response: Remission 79.2%; Tx-naive 55.2%; Active Tx 16.0% https://t.co/Coat9MM05Q
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Mashup Score: 1LNKing eosinophilia and atherothrombosis - 3 hour(s) ago
In this issue of Blood, Dou et al1 reveal a decisive role for hematopoietic lymphocyte adapter protein (LNK) deficiency in promoting eosinophilia, systemic
Source: ashpublications.orgCategories: General Medicine News, Hematologists1Tweet
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Mashup Score: 12T cells take aim in AML: targeting IDH2 - 4 hour(s) ago
In this issue of Blood, Leung et al1 present preclinical findings demonstrating the potential of neoantigen-specific T cells to recognize acute myeloid leu
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Mashup Score: 9Tyrosine kinase inhibitor resistance in de novo BCR::ABL1–positive BCP-ALL beyond kinase domain mutations - 4 hour(s) ago
Imatinib resistance at diagnosis was higher in cells of patients who relapsed vs those in remission after imatinib and chemotherapy.Low levels of BCR::ABL1
Source: ashpublications.orgCategories: General Medicine News, Onc News and JournalsTweet
Full open access article available here: https://t.co/F5cQQPzWyt #mmsm #myeloma @BloodAdvances