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Mashup Score: 34Targeting IDH2R140Q and other neoantigens in acute myeloid leukemia - 19 hour(s) ago
Neoantigens arising from recurrent AML mutations are immunogenic and represent novel immunotherapeutic targets.IDH2R140Q-specific T cells can selectively e
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Mashup Score: 15Prediction of outcomes for high-count monoclonal B lymphocytosis using an epigenetic and immunogenetic signature - 21 hour(s) ago
Individuals with MBL who have a high-risk epigenetic/immunogenetic signature show significant risk of progression to CLL requiring therapy.The signature im
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Mashup Score: 22High microRNA-145 plasma levels are associated with decreased risk of future incident venous thromboembolism: the HUNT study - 23 hour(s) ago
High expression levels of miR-145 in plasma are robustly associated with decreased risk of future incident VTE in a population-based study.miR-145 has the
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Mashup Score: 16miR-145 and incident thromboembolism - 2 day(s) ago
In this issue of Blood, Morelli et al1 report that high plasma levels of miR-145 are associated with decreased risk of incident venous thromboembolism (VTE
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Mashup Score: 53New signature predicts MBL-to-CLL progression - 2 day(s) ago
In this issue of Blood, Abdelbaky and colleagues report the development of a combined epigenetic and immunogenetic signature to study individuals with high
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Mashup Score: 34Durable response after tisagenlecleucel in adults with relapsed/refractory follicular lymphoma: ELARA trial update - 5 day(s) ago
Tisagenlecleucel responses in patients with r/r FL remain highly durable a year after primary analysis; no new safety signals were observed.Low levels of L
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Mashup Score: 42CD371-positive pediatric B-cell acute lymphoblastic leukemia: propensity to lineage switch and slow early response to treatment - 5 day(s) ago
Pediatric CD371-positive B-cell precursor acute lymphoblastic leukemia shows transient lineage switch and slow early response to treatment.Accurate immunop
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Mashup Score: 21Hematopoietic and eosinophil-specific LNK(SH2B3) deficiency promotes eosinophilia and arterial thrombosis - 5 day(s) ago
Eosinophils promote arterial thrombosis in hematopoietic LNK deficiency.Eosinophil LNK is essential in suppression of arterial thrombosis.
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Mashup Score: 40Thrombocytosis - 5 day(s) ago
An asymptomatic 55-year-old woman presented with thrombocytosis discovered 2 years earlier. Laboratory testing revealed the following: hemoglobin 13.1 g/dL, red blood cell count 5.04 × 10 9 /L, hematocrit 41.8%, mean corpuscular volume 83 fL, mean corpuscular hemoglobin concentration 31.3 g/dL, leukocytes 10.87 × 10 9 /L (neutrophils 43%, lymphocytes 45%, monocytes 5%, eosinophils 4%), and platelets 513 × 10 9 /L. Serum ferritin levels were low at 8 ng/mL. Physical examination was unremarkable. Serum
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Mashup Score: 30Volume 143 Issue 17 | Blood | American Society of Hematology - 6 day(s) ago
Blood | 143 | 17 | April 2024
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Neoantigens arising from recurrent AML mutations are immunogenic and represent novel immunotherapeutic targets. https://t.co/d2wkloaIN9 #immunobiologyandimmunotherapy #myeloidneoplasia https://t.co/ye803cZuiE