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Mashup Score: 23Expanding the repertoire reveals recurrent, cryptic, and hematopoietic HLA class I minor histocompatibility antigens - 2 day(s) ago
Expanding the HLA-I–restricted MiHA repertoire by 81 new antigens reveals that MiHAs are often recurrently targeted in multiple patients.Of all 159 MiHAs,
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Mashup Score: 4Human Fc gamma receptor IIIA blockade inhibits platelet destruction in a humanized murine model of ITP - 2 day(s) ago
Human FcγRIII monovalent blocking as a 1-armed antibody or albumin fusion protein are effective in a humanized model of ITP.The monovalent albumin fusion p
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Mashup Score: 11ADAMTS13 recovery in caplacizumab-treated TTP - 2 day(s) ago
In this issue of Blood, Mingot-Castellano et al, on behalf of the Spanish Apheresis Group and the Spanish Thrombotic Thrombocytopenic Purpura Registry, pre
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Mashup Score: 23Applying the EHA/EBMT grading for ICAHT after CAR-T: comparative incidence and association with infections and mortality - 2 day(s) ago
The novel EHA/EBMT grading of ICAHT closely reflects the extent of hematological toxicity following BCMA- and CD19-directed CAR-T therapy.Severe ICAHT was
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Mashup Score: 43Comparison of CAR T-cell vs. bispecific antibody as third- or later-line large B-cell lymphoma therapy: A Meta-analysis - 2 day(s) ago
Key Points. CAR-T cell therapy demonstrates superior efficacy to bispecific antibody in DLBCL treatment, with higher complete response rates.CAR-T cell the
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Mashup Score: 25Defining Primary Refractory Large B-cell Lymphoma - 2 day(s) ago
Key Points. Patients with SD/PD to 1L therapy have lower RRs to 2L therapy and poor outcomes compared to other subgroups of primary refractory diseaseWe ad
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Mashup Score: 1
Arenas and colleagues report that patients with idiopathic multicentric Castleman disease display heightened activation of the mTOR signaling pathway, sugg
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@katie_thomas @jclinicalinvest And we published an extensive mechanistic paper in @BloodJournal in 2020 - https://t.co/3GMu0qDFkQ Though I’ve seen many patients respond to sirolimus (and others that have not responded), it’s still really meaningful to see a study done with so many patients who responded.
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Mashup Score: 25Defining Primary Refractory Large B-cell Lymphoma - 2 day(s) ago
Key Points. Patients with SD/PD to 1L therapy have lower RRs to 2L therapy and poor outcomes compared to other subgroups of primary refractory diseaseWe ad
Source: ashpublications.orgCategories: General Medicine News, Onc News and JournalsTweet
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Mashup Score: 21Long-term Outcomes of Peripheral Blood Stem Cell Unrelated Donors Mobilized with Filgrastim - 2 day(s) ago
Key Points. This was a prospective long term follow-up study including 14530 PBSC and 7123 BM volunteer unrelated donors from the NMDP.PBSC and BM donors h
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Mashup Score: 20Risk of T-cell Malignancy Following CAR T cells in Children, Adolescents and Young Adults - 2 day(s) ago
Adam J. Lamble, Liora M. Schultz, Khanh Nguyen, Emily M Hsieh, Kevin McNerney, Rayne H Rouce, Rebecca A Gardner, Sara Ghorashian, Nirali N Shah, Shannon L.
Source: ashpublications.orgCategories: General Medicine News, Onc News and JournalsTweet
Expanding the HLA-I–restricted MiHA repertoire by 81 new antigens reveals that MiHAs are often recurrently targeted in multiple patients. https://t.co/Q8TbBFTfZs #transplantation #immunobiologyandimmunotherapy https://t.co/zh7CIAg9EJ