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Mashup Score: 23Circadian rhythms in haematological malignancies: therapeutic potential and personalised interventions - 3 day(s) ago
The circadian clock, a fundamental cellular mechanism, regulates the rhythmic expression of numerous genes and biological processes across various organs. Disruptions in this system, driven by genetic or environmental factors, have been reported to be involved in cancer progression. This review explores the role of the circadian clock in cancer hallmarks and its impact on cellular homeostasis within haematological malignancies. Drawing on findings from in vitro, in vivo, and clinical trials, this review highlights the potential of clock genes as diagnostic and prognostic biomarkers, and as therapeutic targets for optimising treatment timing.
Source: www.thelancet.comCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 35
Glofit-GemOx had a significant overall survival benefit compared with R-GemOx, supporting its use in transplant-ineligible patients with relapsed or refractory diffuse large B-cell lymphoma after one or more previous lines of therapy.
Source: www.thelancet.comCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 6Cardiotox2024 - 9 day(s) ago
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Source: cardiotox.netCategories: General Medicine News, Hem/OncsTweet-
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Mashup Score: 13A simple score for clonal cytopenias - 10 day(s) ago
In cases with clonal cytopenia of undetermined significance (CCUS) the challenge of identifying patients at higher risk for disease progression remains sti
Source: ashpublications.orgCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 13A simple score for clonal cytopenias - 10 day(s) ago
In cases with clonal cytopenia of undetermined significance (CCUS) the challenge of identifying patients at higher risk for disease progression remains sti
Source: ashpublications.orgCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 3Artificial intelligence enabled interpretation of ECG images to predict hematopoietic cell transplantation toxicity - 11 day(s) ago
Key PointsAI interpretation of pretransplant ECG images is a novel diagnostic tool to predict transplant arrhythmia risk.AI-ECG prediction of AF also infor
Source: ashpublications.orgCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 19
Key PointsUsing PTCY raised the risk of ECEs but did affect the likelihood of late cardiac toxicity.Strategies to prevent EC are crucial, especially for pa
Source: ashpublications.orgCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 32Autologous stem cell transplantation in T-cell/histiocyte-rich large B-cell lymphoma: EBMT Lymphoma Working Party study - 11 day(s) ago
Key PointsAnalysis of 201 patients with R/R THRLBCL vs 5453 with DLBCL undergoing auto-HCT reveals superior PFS, OS, and relapse incidence for THRLBCL.Auto
Source: ashpublications.orgCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 12Evaluation of prognostic factors in patients with high-risk classical Hodgkin lymphoma undergoing autologous transplantation - 11 day(s) ago
Key PointsThe study shows the safety and long-term efficacy of auto-HCT, even in patients with high-risk cHL who are traditionally considered chemotherapy
Source: ashpublications.orgCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 2
Dra. González Pérez: “La IA identifica patrones en los datos de pacientes con mieloma múltiple que resultan invisibles para el ojo humano”.
Source: isanidad.comCategories: General Medicine News, Hem/OncsTweet
#Hematology Circadian rhythms in haematological malignancies: therapeutic potential and personalised interventions @TheLancet #lymsm #leusm #mmsm #hemonc https://t.co/dUC2U0ZNiq