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    • Mashup Score: 2
      Red blood cells with reduced deformability are selectively cleared from circulation in a mouse model - 1 month(s) ago

      Key PointsSubpopulations of donor RBCs with low deformability are selectively cleared within 24 hours of transfusion in a murine model.Donor RBCs that pers

      Source: ashpublications.org
      Categories: General Medicine News
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        BloodAdvances

        Subpopulations of donor RBCs with low deformability are selectively cleared within 24 hours of transfusion in a murine model. https://t.co/KK5ObpfpEi #redcellsironanderythropoiesis #transfusionmedicine https://t.co/jJ8JEJ37ZC

    • Mashup Score: 7
      Cooperative effect between anti-PF4/H and anti-PF4 antibodies increases cell activation and thrombotic risk in HIT - 1 month(s) ago

      Key PointsAnti-PF4/heparin and anti-PF4 antibodies can cooperate to induce platelet activation, thrombocytopenia, and thrombus formation.The synergistic ef

      Source: ashpublications.org
      Categories: General Medicine News
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        BloodAdvances

        Anti-PF4/heparin and anti-PF4 antibodies can cooperate to induce platelet activation, thrombocytopenia, and thrombus formation. https://t.co/ohhkQTF2KZ #thrombosisandhemostasis https://t.co/bFjmNxR4rz

    • Mashup Score: 34
      Distinct routes of clonal progression in SF3B1-mutant myelodysplastic syndromes - 1 month(s) ago

      Key PointsRUNX1 and STAG2 mutations drive SF3B1-mutant MDS progression, inducing distinct molecular and lineage programs in human HSPCs.High-risk RUNX1 and

      Source: ashpublications.org
      Categories: General Medicine News
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        BloodAdvances

        High-risk RUNX1 and STAG2, but not low-risk TET2, mutations selectively expand different compartments of SF3B1-mutant primitive HSPCs. https://t.co/UGDvJUJzKk #myeloidneoplasia https://t.co/v69YMGpDaf

    • Mashup Score: 0
      Thrombosis, major bleeding, and mortality in 1079 patients with myelofibrosis: a matched population-based study - 2 month(s) ago

      Key PointsThis nationwide study shows that major bleeding and thromboembolic events are more frequent in MF than previously described in other MPNs.The use

      Source: ashpublications.org
      Categories: General Medicine News
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        BloodAdvances

        This nationwide study shows that major bleeding and thromboembolic events are more frequent in MF than previously described in other MPNs. https://t.co/7zfQgztEKh #myeloidneoplasia #thrombosisandhemostasis https://t.co/jqgWGjvWky

    • Mashup Score: 19
      Clinical outcomes in older adults treated outside clinical studies: highlighting the octogenarian experience - 2 month(s) ago

      Key PointsTriplet regimens provide longer TTNT and improved OS than doublets in Octos.The introduction of daratumumab-based regimens resulted in significan

      Source: ashpublications.org
      Categories: General Medicine News
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      • Profile photo of 	BloodAdvances
        BloodAdvances

        The introduction of daratumumab-based regimens resulted in significantly longer TTNT. https://t.co/gmiwkruzQi #plasmacelldisorders #healthservicesandoutcomes https://t.co/hV6VQKdiCk

    • Mashup Score: 19
      Clinical outcomes in older adults treated outside clinical studies: highlighting the octogenarian experience - 2 month(s) ago

      Key PointsTriplet regimens provide longer TTNT and improved OS than doublets in Octos.The introduction of daratumumab-based regimens resulted in significan

      Source: ashpublications.org
      Categories: General Medicine News
      Tweet Tweets with this article
      • Profile photo of 	BloodAdvances
        BloodAdvances

        The introduction of daratumumab-based regimens resulted in significantly longer TTNT. https://t.co/gmiwkruzQi #plasmacelldisorders #healthservicesandoutcomes https://t.co/hV6VQKdiCk

    • Mashup Score: 34
      Clonal relatedness as a prognostic marker in Richter transformation of chronic lymphocytic leukemia: a systematic review - 2 month(s) ago

      Abstract. The disease shift of chronic lymphocytic leukemia (CLL) to diffuse large B-cell lymphoma (DLBCL), so-called Richter transformation (RT), is a cat

      Source: ashpublications.org
      Categories: General Medicine News, Onc News and Journals
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      • Profile photo of 	BloodAdvances
        BloodAdvances

        The disease shift of chronic lymphocytic leukemia to diffuse large B-cell lymphoma, so-called Richter transformation, is a catastrophic clinical event. https://t.co/kI4OnsUmdf #lymphoidneoplasia https://t.co/ZtNaFd8Sr3

    • Mashup Score: 0
      Implementing ASH’s guidelines for acute medical care for incarcerated children and adults with sickle cell disease - 2 month(s) ago

      Abstract. Between 2019 and 2021, the American Society of Hematology (ASH) developed clinical guidelines for managing sickle cell disease (SCD), covering ac

      Source: ashpublications.org
      Categories: General Medicine News
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      • Profile photo of 	BloodAdvances
        BloodAdvances

        Implementing ASH’s guidelines for acute medical care for incarcerated children and adults with sickle cell disease https://t.co/QW5Bx7ovd8 #healthservicesandoutcomes #redcellsironanderythropoiesis

    • Mashup Score: 9
      Clonal relatedness as a prognostic marker in Richter transformation of chronic lymphocytic leukemia: a systematic review - 2 month(s) ago

      Abstract. The disease shift of chronic lymphocytic leukemia (CLL) to diffuse large B-cell lymphoma (DLBCL), so-called Richter transformation (RT), is a cat

      Source: ashpublications.org
      Categories: General Medicine News, Onc News and Journals
      Tweet Tweets with this article
      • Profile photo of 	BloodAdvances
        BloodAdvances

        Clonal relatedness as a prognostic marker in Richter transformation of chronic lymphocytic leukemia: a systematic review https://t.co/HMHbmJio7S #lymphoidneoplasia https://t.co/cfn0A00lI8

    • Mashup Score: 11
      Characteristics and outcomes of patients with double refractory and double exposed chronic lymphocytic leukemia - 2 month(s) ago

      Key PointsThe median OS of patients with DR CLL whose disease progressed during BTK and BCL2 inhibition was 2.2 years.DE CLL represented a less aggressive

      Source: ashpublications.org
      Categories: General Medicine News
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      • Profile photo of 	BloodAdvances
        BloodAdvances

        The median OS of patients with DR CLL whose disease progressed during BTK and BCL2 inhibition was 2.2 years. https://t.co/qRvh5pLb7B #lymphoidneoplasia https://t.co/EUf6rZ9XSC

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    Blood Advances

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    Blood Advances, a digital open-access journal from the American Society of Hematology, @ASH_hematology

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