New opportunities to prevent inequalities in child development?
The in-utero metabolic environment is now a widely researched and well established focus in the study of the developmental origins of health and disease. However, research has focused more on metabolic outcomes than on neurodevelopmental outcomes in children. The systematic review and meta-analysis published in The Lancet Diabetes & Endocrinology by Wenrui Ye and colleagues1 adds to the growing evidence indicating a negative impact of maternal hyperglycaemia on neurodevelopmental outcomes; this finding has implications for clinicians, researchers, and policy makers involved in improving maternal and child health.