Human γδ T cell sensing of AMPK-dependent metabolic tumor reprogramming through TCR recognition of EphA2
A γδ TCR senses metabolic tumor reprogramming through recognition of EphA2.
A γδ TCR senses metabolic tumor reprogramming through recognition of EphA2.
Targeting PD-1+ cells promotes immune tolerance via peripheral clonal deletion of antigen-specific T cells.
A subset of CD8 T cells with a terminally exhausted epigenetic profile expressed IFN-γ, granzymes, and perforin in bone marrow.
Targeting of GALT by anti-α4β7 therapy is associated with therapeutic responses in ulcerative colitis.
A subset of CD8 T cells with a terminally exhausted epigenetic profile expressed IFN-γ, granzymes, and perforin in bone marrow.
Allogeneic CAR-DNTs with minimal genetic modification show potent anti-tumor activity without off-tumor toxicities.
Spatially resolved profiling of the melanoma microenvironment reveals correlates of response to immune checkpoint inhibitors.
Targeting of GALT by anti-α4β7 therapy is associated with therapeutic responses in ulcerative colitis.
The transcriptional regulator Trim33 controls Flt3L-driven dendritic cell differentiation.
Division of labor among resident tissue macrophages is vital for proper tissue function during homeostasis.
The transcriptional regulator Trim33 controls Flt3L-driven dendritic cell differentiation.