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Mashup Score: 7An armed anti-immunoglobulin light chain nanobody protects mice against influenza A and B infections - 10 month(s) ago
A nanobody-based composite recruits polyclonal immunoglobulins, attracts immune effectors, and kills influenza virus–infected cells.
Source: Science ImmunologyCategories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 36Rewilding of laboratory mice enhances granulopoiesis and immunity through intestinal fungal colonization - 10 month(s) ago
Fungal colonization of lab mice, through release into the wild or inoculation with Candida albicans, enhances granulopoiesis.
Source: Science ImmunologyCategories: Future of Medicine, Latest HeadlinesTweet-
Exposure to fungi can help sterile laboratory mice better model specific features of the human immune system, finds new research in @SciImmunology. https://t.co/6YRcmEk9fI https://t.co/vjgkGHzHGw
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Mashup Score: 0Activation of regulatory dendritic cells by Mertk coincides with a temporal wave of apoptosis in neonatal lungs - 10 month(s) ago
Mertk promotes maturation of regulatory dendritic cells in neonatal lungs.
Source: Science ImmunologyCategories: Future of Medicine, Latest HeadlinesTweet-
During lung maturation in newborn mice, a distinct population of dendritic cells that can suppress killer T cells appears during the first two weeks of life, a new @SciImmunology study finds. https://t.co/chHnZp5xXI https://t.co/kFzhRdamHM
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Mashup Score: 4Human γδ T cell sensing of AMPK-dependent metabolic tumor reprogramming through TCR recognition of EphA2 - 10 month(s) ago
A γδ TCR senses metabolic tumor reprogramming through recognition of EphA2.
Source: Science ImmunologyCategories: Allergy-Immunology, Latest HeadlinesTweet-
Metabolic changes that occur in cells during #cancer can help human γδ T cells detect antigens released by tumors, unleashing the cells against the cancer, suggested a 2021 @univbordeaux_EN @CRUK_Birmingham @CNRS study in human cells. 📄: https://t.co/MrZUcH72Ut #WeekendReads https://t.co/Pi3NsGitX3
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Mashup Score: 25Contents | Science Immunology 8, 82 - 1 year(s) ago
Focus The coevolution of multiple specialized T follicular regulatory cell subsets has led to fine-tuning of human germinal center responses. Research Articles A five-marker signature identifies scar-associated macrophages that differentiate in response to GM-CSF,…
Source: Science ImmunologyCategories: Allergy-Immunology, Latest HeadlinesTweet-
The April cover of Science #Immunology is out! This month, a study describes the developmental lineage of T follicular regulatory cells isolated from human tonsils. Other pieces examine macrophages behind fibrosis and neoantigens for cancer vaccines. https://t.co/Xz78eRmDlz https://t.co/LnoCMf7wtq
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Mashup Score: 25Contents | Science Immunology 8, 81 - 1 year(s) ago
Science Immunology Volume 8|Issue 81|Mar 2023 ONLINE COVER Glycoengineering the Tip of the Spear. This month’s cover depicts cellular soldiers (blue myeloid cells at the left and green T cells at the right) rushing to battle cancer cells. Leading the charge is an Fc-enhanced form of an anti–PD-L1 checkpoint blockade antibody. Using mice humanized to express human Fcγ…
Source: Science ImmunologyCategories: Allergy-Immunology, Latest HeadlinesTweet-
The March issue of Science #Immunology is out now! The cover study shares findings that could help revamp human IgG1 Fc-engineering strategies to enhance future generations of anti-PD-L1 #cancer #immunotherapy drugs: https://t.co/v9mFAeSX4h https://t.co/xNPWMaJw10
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Mashup Score: 7Contents | Science Immunology 8, 80 - 1 year(s) ago
Science Immunology Volume 8|Issue 80|Feb 2023 ONLINE COVER Tumor-infiltrating Lymphocytes on JET Patrol. This month’s cover depicts T lymphocytes specific for tumor neoantigens near a cancer cell (yellow) displaying neoantigen peptides on a subset of its cell-surface MHC molecules. JETs (Junctions between Exons and Transposable elements) are a new class of cancer-associated…
Source: Science ImmunologyCategories: Allergy-Immunology, Latest HeadlinesTweet-
The February issue of Science #Immunology is out! The cover features insights from two new studies that explore how recurrent TE-exon splicing junctions could be potentially used to improve #cancer immunotherapies: https://t.co/OJHjmF0JJE https://t.co/BRnFgNoGel
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Mashup Score: 6Science Immunology | AAAS - 1 year(s) ago
Science Immunology—publishing critical advances in all areas of immunological research, including new tools and techniques.
Source: Science ImmunologyCategories: Healthcare Professionals, Latest HeadlinesTweet-
RT @IforRWilliams: NEW for 2023 on the @SciImmunology website is the dedicated CANCER IMMUNOLOGY block. 🔗➡️https://t.co/rpcxdGgLOz Scroll d…
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Mashup Score: 1Science Immunology | AAAS - 1 year(s) ago
Science Immunology—publishing critical advances in all areas of immunological research, including new tools and techniques.
Source: Science ImmunologyCategories: Allergy-Immunology, Latest HeadlinesTweet-
RT @IforRWilliams: NEW for 2023 on the @SciImmunology website is the dedicated CANCER IMMUNOLOGY block. 🔗➡️https://t.co/rpcxdGgLOz Scroll d…
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Mashup Score: 2Contents | Science Immunology 8, 79 - 1 year(s) ago
Science Immunology Volume 8|Issue 79|Jan 2023 ONLINE COVER Spontaneous Eosinophilic Esophagitis in Mice. This month’s cover shows esophageal cross-sections from 24-week-old mice stained with hematoxylin and eosin (left side) or an immunoperoxidase stain for the eosinophil granule protein major basic protein (right side). Laky et al. found that knock-in mice heterozygous for…
Source: Science ImmunologyCategories: Allergy-Immunology, Latest HeadlinesTweet-
The January issue of Science #Immunology is out! The cover study shows how dysfunctional epithelial cells can drive eosinophilic esophagitis in mice. Other work explores TSLP-blockade therapies for severe #asthma. https://t.co/eAIRExRduA https://t.co/InzCpaCHYI
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Using a new therapeutic strategy, researchers developed a nanobody attached to a flu anti-viral drug to successfully enhance mice’s immune responses and reduce symptoms during influenza A and B infections. @BalligandThomas @PloeghLab https://t.co/EJI1kbpfT5 https://t.co/qx0hFdeXS7