Frontiers | Modifying reaction time tasks parameters in the automated IntelliCage identifies heightened impulsivity and impaired attention in the 3xTg-AD model of Alzheimer’s disease
1 Arizona State University-Banner Neurodegenerative Disease Research Center at the Biodesign Institute, Arizona State University, Tempe, AZ, United States 2 School of Life Sciences, Arizona State University, Tempe, AZ, United States 3 Arizona Alzheimer’s Consortium, Phoenix, AZ, United States Background: The 3xTg-AD transgenic mouse model of Alzheimer’s disease (AD) is an important tool to investigate the relationship between development of pathological amyloid- β (A β) and tau, neuroinflammation, and