Frontiers | Excitatory neuron-prone prion propagation and excitatory neuronal loss in prion-infected mice
1 Laboratory of Veterinary Hygiene, Faculty of Veterinary Medicine, Graduate School of Infectious Diseases, Hokkaido University, Sapporo, Japan 2 One Health Research Center, Hokkaido University, Sapporo, Japan 3 Global Station for Zoonosis Control, Global Institute for Collaborative Research and Education, Hokkaido University, Sapporo, Japan The accumulation of a disease-specific isoform of prion protein (PrP Sc) and histopathological lesions, such as neuronal loss, are unevenly distributed in the brains
