CD123 to the rescue
A 68-year-old woman with a history of discoid lupus erythematosus presented with multiple subcutaneous nodules on the breast and upper extremities. An incisional biopsy was performed due to concern for subcutaneous panniculitis-like T-cell lymphoma (SPTCL). Hematoxylin-eosin staining showed a dense lymphoid infiltrate (panel A: original magnification ×40; panel C: original magnification ×400) rimming adipocytes, with scattered plasma cells involving the deep dermis and subcutaneous tissue (panel B: