Bidirectional histone monoaminylation dynamics regulate neural rhythmicity
Nature – TG2 functions as an eraser and exchanger of H3 monoaminylations, including histaminylation of Gln5 of histone H3.
Nature – TG2 functions as an eraser and exchanger of H3 monoaminylations, including histaminylation of Gln5 of histone H3.
Selective modifications in the expression or function of dendritic ion channels regulate the propagation of synaptic inputs and determine the intrinsic excitability of a neuron.…
Nature – A family of host-derived bile acid–methylcysteamine conjugates functions as FXR antagonists, forming part of a microbiota-dependent metabolic network that regulates FXR-dependent…
Dr. Angela Curcio of Columbia University Medical Center and a member of JCN and CNO’s Residents & Fellows Board interviews Dr. Rana Said of UT…
1 Graduate School, Beijing University of Chinese Medicine, Beijing, China 2 Department of Neurology, China-Japan Friendship Hospital, Beijing, China 3 Department of Orthopedics, Handan Chinese…
Background and ObjectivesSickle cell disease (SCD) is a hemoglobinopathy resulting in hemoglobin-S production, hemolytic anemia, and elevated stroke risk. Treatments include oral hydroxyurea, blood transfusions,…
Burnout has become an unsustainable aspect of medicine in today’s fast-paced and insurance-driven world, with such burdens including replacement costs of two to three times…
Nature Communications – Colorectal cancer has been linked to multiple environmental factors, however, the role of diet remains incompletely understood. Here, the authors complete a…
Podcast Episode · Practical Neurology Podcast · 01/08/2025 · 45m
Nature Communications – Exiting germinal zones (GZ) is key for neuronal maturation, but how cells integrate external and internal cues to achieve it is unclear.…