Frontiers | Opioidergic tuning of social attachment: reciprocal relationship between social deprivation and opioid abuse
1 Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, United States 2 Nancy Pritzker Laboratory, Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, United States Individuals misusing opioids often report heightened feelings of loneliness and decreased ability to maintain social connections. This disruption in social functioning further promotes addiction, creating a cycle in which increasing isolation drives drug use. Social factors also