Learning to mellow out GVHD
In this issue of Blood, Yuan et al demonstrated that cannabinoids modulate the adoptive and innate immune responses involved in the regulation of acute and chro
In this issue of Blood, Yuan et al demonstrated that cannabinoids modulate the adoptive and innate immune responses involved in the regulation of acute and chro
In a pair of Special Reports, Gökbuget and colleagues present updated European Leukemia Net (ELN) consensus reports on (1) the diagnosis, prognostic factor
Transfusion of red blood cells (RBCs) can be lifesaving for individuals living with sickle cell disease (SCD). However, alloimmunization following transfus
Key Points. Pretransplant single dose CD45-ADC conditioning effectively promoted alloengraftment with low toxicity in 3 Fanconi anemia mouse models.Donor T cell
Key Points. Previous studies showed that fludarabine PK exposure is associated with key outcomes in pediatric patients after tisagenlecleucel.In adults receivin
The success of hematopoietic transplant for hemoglobinopathies and hematological malignancies has been accompanied by the new challenge of how to identify,
RLYB331 is a human antibody that increases hepcidin, reduces iron overload, and ameliorates ineffective erythropoiesis in β-thalassemiaCombination with RAP
Transfusion of red blood cells (RBCs) can be lifesaving for individuals living with sickle cell disease (SCD). However, alloimmunization following transfus
Molecular MRD after induction chemotherapy identifies patients with NPM1 AML who benefit from allogeneic transplant in first remission.Patients achieving M
Molecular MRD after induction chemotherapy identifies patients with NPM1 AML who benefit from allogeneic transplant in first remission.Patients achieving M
SOX11 directly binds, via its HMG domain, to SAMHD1, reducing its tetramerization and inhibiting its ara-CTPase activity in MCL.The noncompetitive inhibito