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Mashup Score: 0ByteMed #3: AI in healthcare roadmap, 700.000 wearbale data and GPT4 better than residents - 12 day(s) ago
The algorithm journey map: a tangible approach to implementing AI solutions in healthcare When integrating AI tools in healthcare settings, complex interactions between technologies and primary users are not always fully understood or visible. This deficient and ambiguous understanding hampers attempts by healthcare organizations to adopt AI/ML, and it also creates new challenges for researchers to identify opportunities for simplifying adoption and developing best practices for the use of AI-based solutions. Our study fills this gap by documenting the process of designing, building, and maintaining an AI solution called SepsisWatch at Duke University Health System. We conducted 20 interviews with the team of engineers and scientists that led the multi-year effort to build the tool, integrate it into practice, and maintain the solution. This “Algorithm Journey Map” enumerates all social and technical activities throughout the AI solution’s procurement, development, integration, and ful
Source: albertomussetti.substack.comCategories: General Medicine News, Hematologists1Tweet
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Mashup Score: 26
PURPOSE Recurrence of blood malignancy is the major cause of hematopoietic cell transplant failure. HLA class II molecules play a fundamental role in antitumor responses but the role of class II haplotypes is not known. METHODS HLA-DR, -DQ, -DM, and -DO allele variation was determined in 1,629 related haploidentical transplants to study the clinical significance of individual molecules and haplotypes. RESULTS Outcome correlated with patient and donor variation for HLA-DRβ residue 86 (Gly/Val), HLA-DQ (G1/G2) heterodimers, and donor HLA-DM (DM11,11/nonDM11,11) molecules, and depended on patient-donor mismatching. Risks of relapse were lower for DRβ-86 GlyGly patients when the donor was GlyVal (hazard ratio [HR], 0.46 [95% CI, 0.30 to 0.68]; P < .001); GlyVal patients benefited from HLA-DRB1–matched donors, whereas no donor was superior to another for ValVal patients. G1G2 patients with G1G2-mismatched donors had lower relapse. Transplantation from donors with DMα residue 184 ArgHis was
Source: ascopubs.orgCategories: General Medicine News, Hematologists1Tweet
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Mashup Score: 0ByteMed #2: AI Roadmap, GPT4 in cancer center and machine learning preaasessment for pre-eclampsia - 22 day(s) ago
The AI Maturity Roadmap: A Framework for Effective and Sustainable AI in Health Care Thanks for reading ByteMed – AI and Medicine! Subscribe for free to receive new posts and support my work. BACKGROUND Though many health systems are starting to deploy artificial intelligence (AI) and machine learning for clinical applications, there is limited guidance available to benchmark progress and assess maturity on a sector-wide scale.
Source: albertomussetti.substack.comCategories: General Medicine News, Hematologists1Tweet
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Mashup Score: 2ByteMed #2: AI Roadmap, GPT4 in cancer center and machine learning preaasessment for pre-eclampsia - 23 day(s) ago
The AI Maturity Roadmap: A Framework for Effective and Sustainable AI in Health Care Thanks for reading ByteMed – AI and Medicine! Subscribe for free to receive new posts and support my work. BACKGROUND Though many health systems are starting to deploy artificial intelligence (AI) and machine learning for clinical applications, there is limited guidance available to benchmark progress and assess maturity on a sector-wide scale.
Source: albertomussetti.substack.comCategories: General Medicine News, Hematologists1Tweet
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Mashup Score: 41How I reduce and treat posttransplant relapse of MDS - 23 day(s) ago
Posttransplant relapse is the major cause of failure when patients undergo allogeneic stem cell transplant as a cure for myelodysplastic syndromes (MDS). M
Source: ashpublications.orgCategories: General Medicine News, Hematologists1Tweet
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Mashup Score: 13CD70-specific CAR-NK cells expressing IL-15 for the treatment of CD19-negative B cell malignancy - 23 day(s) ago
Key Points. CD70-specific CAR-NK cells secrete IL-15, specifically lyse both CD19 positive and CD19 negative B cell lymphoma in vitro and in vivoTwo doses
Source: ashpublications.orgCategories: General Medicine News, Hematologists1Tweet
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Mashup Score: 22
CAR-T therapies have established themselves as the standard of care in relapsed and refractory haematologic malignancies for a variety of indications. With an increasing number of patients and approved CAR-Ts, there is a growing body of evidence on the spectrum of complications, which are distinct from complications of hematopoietic cell transplantation. This educational course will cover both common and rare complications and ongoing changes in the practices of monitoring, prophylaxis and treatment of
Source: www.ebmt.orgCategories: General Medicine News, Hematologists1Tweet
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Mashup Score: 2AI in Cancer Care - 27 day(s) ago
The prelude to a new era
Source: albertomussetti.substack.comCategories: General Medicine News, Hematologists1Tweet
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Mashup Score: 5Coping in patients with hematologic malignancies undergoing hematopoietic cell transplantation - 29 day(s) ago
Coping strategies before HCT are associated with pre-HCT quality-of-life and psychological distress.Supportive care interventions during HCT to promote app
Source: ashpublications.orgCategories: General Medicine News, Hematologists1Tweet
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Mashup Score: 13Fully human anti-CD19 CAR T cells derived from systemic lupus erythematosus patients exhibit cytotoxicity with reduced inflammatory cytokine production - 1 month(s) ago
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the formation of autoantibodies that lead to immune complex-induced inflammation in an array of different organs including the kidneys, heart, lungs and skin. The pathogenesis of SLE is complex and relies on genetic, endogenous, environmental and immunoregulatory factors1. The central role of B cells in SLE is supported by the presence of B cells in diseased tissues, clonal expansion and plasmablast generation. Monoclonal antibodies that disrupt B cell activation or deplete B cells have been used to treat autoimmune diseases like SLE.
Source: www.astctjournal.orgCategories: General Medicine News, Hematologists1Tweet
ByteMed #3: AI in healthcare roadmap, 700.000 wearbale data and GPT4 better than residents https://t.co/aFEZZ3zKtq