Volume 145 Issue 7 | Blood | American Society of Hematology
Blood | 145 | 7 | February 2025
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Clinical Outcomes in Elderly Patients Treated Outside Clinical Studies: Highlighting the Octogenarian Experience
Key Points. Triplets provide longer TTNT and improved OS than doublets in Octogenarians.The introduction of daratumumab-based regimens resulted in signific
Cullin-5 controls the number of megakaryocyte-committed stem cells to prevent thrombocytosis in mice
Key PointsCul5 regulates production of megakaryocyte-committed stem cells to prevent excess megakaryopoiesis.Cul5-deficient megakaryopoiesis is largely ind
Childhood Langerhans cell histiocytosis hematological involvement: severity associated with BRAFV600E loads
Key PointsLCH-HI is life threatening, defined as hemoglobin ≤7 g/dL and/or platelets ≤20 × 109/L.LCH-HI severity, associated with BRAFV600E variant and mac
Air pollution is associated with increased risk of venous thromboembolism: the Multi-Ethnic Study of Atherosclerosis
Key Points:Air pollution exposure is common, and may increase risk of developing blood clots.Greater long-term exposure to air pollution (ie, PM2.5, NOxNO2
TIFAB modulates metabolic pathways in KMT2A::MLLT3−induced AML through HNF4A
Key PointsTIFAB regulates oxidative phosphorylation in AML stem/progenitor cells.HNF4A, a newly identified downstream target of TIFAB, rescues the metaboli
ALK+ anaplastic large cell lymphoma expressing CD33 and myeloid nuclear differentiation antigen
Miguel Gonzalez Mancera, Oscar Silva; ALK + anaplastic large cell lymphoma expressing CD33 and myeloid nuclear differentiation antigen. Blood 2025; 145 (10): 1098. doi: https://doi.org/10.1182/blood.2024027618…
Role of molecular alterations in transplantation decisions for patients with primary myelofibrosis
Key PointsPatients with high MIPSS70 scores benefit from transplantation.Patients with intermediate MIPSS70 scores may benefit from transplantation if thei
Blood Podcast | Blood | American Society of Hematology
Blood Podcast | Blood | American Society of Hematology Blood Podcast The editors of Blood are pleased to introduce a podcast series, published weekly…
Approaching hypercalcemia in monoclonal gammopathy of undetermined significance: insights from the iStopMM screening study
Key PointsHypercalcemia in MGUS rarely indicates progression to MM; no isolated hypercalcemia indicating progression was observed.Hypercalcemia cases in MG
Official SUFS Events
These are the state capitals and major cities (alphabetized by state) hosting official Stand Up for Science events. If your city is listed below, a…
