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Mashup Score: 25
We feel that we perceive events in the environment as they unfold in real-time. However, this intuitive view of perception is impossible to implement in the nervous system due to biological constraints such as neural transmission delays. I propose a new way of thinking about real-time perception: at any given moment, instead of representing a single timepoint, perceptual mechanisms represent an entire timeline. On this timeline, predictive mechanisms predict ahead to compensate for delays in incoming sensory input, and reconstruction mechanisms retroactively revise perception when those predictions do not come true.
Source: www.cell.comCategories: General Medicine News, Future of MedicineTweet
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Mashup Score: 116How Men and Women Rate Each Other on Dating Websites - 8 day(s) ago
Men find women more attractive than women find men
Source: www.stevestewartwilliams.comCategories: General Medicine News, Future of MedicineTweet
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Mashup Score: 7
Nature Neuroscience – The layout of cortical systems varies across people, which is assumed to be largely due to border shifts between nearby systems. Dworetsky et al. reveal a qualitatively…
Source: www.nature.comCategories: General Medicine News, Future of MedicineTweet
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Mashup Score: 5
Au sommaire de votre magazine, les principales découvertes et avancées scientifiques sont décryptées par nos journalistes.
Source: www.science-et-vie.comCategories: General Medicine News, Future of MedicineTweet
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Mashup Score: 4
Sonic hedgehog (Shh) is an axon guidance molecule that can act as either a chemorepellent or a chemoattractant, depending on the neuron type and their developmental stage. In the developing spinal cord, Shh initially attracts commissural axons to the floor plate and later induces their repulsion after they cross the midline. In the developing visual system, Shh repels ipsilateral retinal ganglion cell (iRGC) axons at the optic chiasm. Although Shh requires the endocytic adaptor Numb for attraction of commissural neurons, the molecular mechanisms underlying Shh’s dual function in attraction and repulsion are still unclear. In this study, we investigate whether Numb also regulates repulsive axon guidance. We show that Numb is essential for two Shh-mediated repulsion processes: iRGC axon repulsion at the optic chiasm and antero-posterior commissural axon repulsion in the spinal cord. Therefore, Numb is required for Shh-mediated attraction and repulsion. These results position Numb as a ce
Source: www.biorxiv.orgCategories: General Medicine News, Future of MedicineTweet
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Mashup Score: 5Mating proximity blinds threat perception - 9 day(s) ago
Romantic engagement can bias sensory perception. This ’love blindness’ reflects a common behavioral principle across organisms: favoring pursuit of a coveted reward over potential risks. In the case of animal courtship, such sensory biases may support reproductive success but can also expose individuals to danger, such as predation. How do neural networks balance the trade-off between risk and reward? Here, we discover a dopamine-governed filter mechanism in male Drosophila that reduces threat perception as courtship progresses. We show that during early courtship stages, threat-activated visual neurons inhibit central courtship nodes via specific serotonergic neurons. This serotonergic inhibition prompts flies to abort courtship when they see imminent danger. However, as flies advance in the courtship process, the dopaminergic filter system reduces visual threat responses, shifting the balance from survival to mating. By recording neural activity from males as they approach mating, we
Source: www.biorxiv.orgCategories: General Medicine News, Future of MedicineTweet
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Mashup Score: 2AN EMERGING BOOK - 9 day(s) ago
AN EVOLVING TABLE OF CONTENTS 0. Introduction 1. Manifesto 2. 12 Theses 3. The Age of Machines 4. Death to the Demon 5. A Large World 6. Mechanistic Maps 7. Church-Turing-Deutsch 8. The Lost…
Source: www.expandingpossibilities.orgCategories: General Medicine News, Future of MedicineTweet
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Mashup Score: 32Forms of life, forms of mind | Dr. Michael Levin | Farewell, Dan Dennett, I will really miss you. - 9 day(s) ago
A farewell to philosopher Daniel C. Dennett.
Source: thoughtforms.lifeCategories: General Medicine News, Future of MedicineTweet
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Mashup Score: 11Developmental brain dysfunction: revival and expansion of old concepts based on new genetic evidence - 9 day(s) ago
Neurodevelopmental disorders can be caused by many different genetic abnormalities that are individually rare but collectively common. Specific genetic causes, including certain copy number variants and single-gene mutations, are shared among disorders …
Source: www.ncbi.nlm.nih.govCategories: General Medicine News, Future of MedicineTweet
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Mashup Score: 16A phenotypic spectrum of autism is attributable to the combined effects of rare variants, polygenic risk and sex - PubMed - 9 day(s) ago
The genetic etiology of autism spectrum disorder (ASD) is multifactorial, but how combinations of genetic factors determine risk is unclear. In a large family sample, we show that genetic loads of rare and polygenic risk are inversely correlated in cases and greater in females than in males, consist …
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, Future of MedicineTweet
RT @leafs_s: Trends in Cognitive Sciences Perception in real-time: predicting the present, reconstructing the past https://t.co/70kuBp6pYB