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Mashup Score: 532多様なコロナ後遺症 国内発生4年 不明だった実態、徐々に明らかに:朝日新聞デジタル - 4 month(s) ago
新型コロナウイルスへの感染後に続く「後遺症」。疲労感や呼吸困難、集中力の低下など症状や続く期間は人によって様々で、原因などまだ分からないことも多かった。国内で感染者が確認されて4年。最新の研究により…
Source: www.asahi.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 223Vaccination after developing long COVID: Impact on clinical presentation, viral persistence, and immune responses - PubMed - 4 month(s) ago
Our study shows higher pro-inflammatory responses associated with PCC symptoms and brings forward a possible role for vaccination in mitigating PCC symptoms by decreasing systemic inflammation. We also observed persistence of viral products independent of vaccination that could be involved in perpet …
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, General HCPsTweet
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Mashup Score: 339Rapid activation of IL-2 receptor signaling by CD301b+DC-derived IL-2 dictates the outcome of helper T cell differentiation - 6 month(s) ago
Effector T helper (Th) cell differentiation is fundamental to functional adaptive immunity. Different subsets of dendritic cells (DCs) preferentially induce different types of Th cells, but the fate instruction mechanism for Th type 2 (Th2) differentiation remains enigmatic, as the critical DC-derived cue has not been clearly identified. Here, we show that CD301b+DCs, a major Th2-inducing DC subset, drive Th2 differentiation through cognate interaction by ‘kick-starting’ IL-2 receptor signaling in CD4T cells. Mechanistically, CD40 engagement induces IL-2 production selectively from CD301b+DCs to maximize CD25 expression in CD4 T cells, which is required specifically for the Th2 fate decision. On the other hand, CD25 in CD301b+DCs facilitates directed action of IL-2 toward cognate CD4T cells. Furthermore, CD301b+DC-derived IL-2 skews CD4T cells away from the T follicular helper fate. These results highlight the critical role of DC-intrinsic CD40–IL-2 axis in bifurcation of Th cell fate.
Source: www.biorxiv.orgCategories: General Medicine News, Infectious DiseaseTweet
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Mashup Score: 872ME/CFS, Long COVID, and Chronic Lyme Disease Research Aided by $3 Million in Donor Gifts to Yale School of Medicine - 7 month(s) ago
Yale School of Medicine has received major gifts to support Professor Akiko Iwasaki’s research into Long COVID, chronic Lyme disease, and ME/CFS.
Source: medicine.yale.eduCategories: General Medicine News, General HCPsTweet
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Mashup Score: 26*Yale University Giving - 7 month(s) ago
Step 1 of 5: Make a Gift Step 2 of 5: Current: Gift Details Step 3 of 5: Billing Step 4 of 5: Review Step 5 of 5: Finish Make a…
Source: secure.yale.imodules.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 6MCDB Special Seminar - 7 month(s) ago
Dr. Charles Rice
Source: yale.hosted.panopto.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 24Science In Action - Returning to the North Pole - BBC Sounds - 8 month(s) ago
Ice breaker Polarstern returns to the Arctic visiting sites last explored in 2012.
Source: www.bbc.co.ukCategories: Healthcare Professionals, Latest HeadlinesTweet
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Mashup Score: 73Evidence of leaky protection following COVID-19 vaccination and SARS-CoV-2 infection in an incarcerated population - 9 month(s) ago
Nature Communications – Measuring an individual’s level of exposure to COVID-19 is challenging, and it is therefore unclear whether high exposure may impact immunity. Here, the authors…
Source: www.nature.comCategories: Healthcare Professionals, Latest HeadlinesTweet
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Mashup Score: 177Postacute sequelae of COVID-19 at 2 years - 9 month(s) ago
Nature Medicine – Analysis of data from the US Department of Veterans Affairs showed that 2 years after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, risk for most…
Source: www.nature.comCategories: Healthcare Professionals, Latest HeadlinesTweet
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Mashup Score: 58
Inhaled polymer nanoparticles achieve high mRNA expression in the lung and induce protective immunity against SARS-CoV-2.
Source: www.science.orgCategories: Healthcare Professionals, Latest HeadlinesTweet
多様なコロナ後遺症 国内発生4年 不明だった実態、徐々に明らかに:朝日新聞デジタル Mount Sinai-Yale long COVID (MY-LC) の研究内容が紹介されています。@PutrinoLab https://t.co/Qy1HfIfj4p