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Mashup Score: 4Cardiogenic shock - 9 day(s) ago
Cardiogenic shock is a complex syndrome defined by systemic hypoperfusion and inadequate cardiac output arising from a wide array of underlying causes. Although the understanding of cardiogenic shock epidemiology, specific subphenotypes, haemodynamics, and cardiogenic shock severity staging has evolved, few therapeutic interventions have shown survival benefit. Results from seminal randomised controlled trials support early revascularisation of the culprit vessel in infarct-related cardiogenic shock and provide evidence of improved survival with the use of temporary circulatory support in selected patients.
Source: www.thelancet.comCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 5Finerenone: A Third-Generation MRA and Its Impact on Cardiovascular Health—Insights from Randomized Controlled Trials - 10 day(s) ago
Introduction: Finerenone, a third-generation non-steroidal mineralocorticoid receptor antagonist (MRA), offers a targeted approach to managing cardiovascular outcomes, particularly in patients with chronic kidney disease (CKD) and type 2 diabetes (T2D). Unlike traditional MRAs such as spironolactone and eplerenone, which can cause off-target hormonal side effects and hyperkalemia, Finerenone selectively binds to mineralocorticoid receptors, reducing these risks. Recent randomized controlled trials have demonstrated Finerenone’s potential to improve cardiovascular outcomes, making it a promising alternative in the management of heart failure and other cardiovascular conditions associated with CKD and T2D. Methods: We conducted a scoping review using PRISMA guidelines. A search for “Finerenone” in the PubMed, Embase, and Cochrane Library databases included randomized controlled trials (RCTs), post hoc analyses, and relevant meta-analyses on cardiovascular outcomes. Data were synthesized
Source: www.mdpi.comCategories: General Medicine News, CardiologistsTweet-
https://t.co/CfxqtyVG4R
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Mashup Score: 0Update on Diagnosis and Management of Kawasaki Disease: A Scientific Statement From the American Heart Association | Circulation - 11 day(s) ago
Kawasaki disease (KD), an acute self-limited febrile illness that primarily affects children <5 years old, is the leading cause of acquired heart disease in developed countries, with the potential of leading to coronary artery dilation and coronary artery aneurysms in 25% of untreated patients. This update summarizes relevant clinical data published since the 2017 American Heart Association scientific statement on KD related to diagnosis, cardiac imaging in acute KD treatment, and long-term management. Criteria defining North American patients at high risk for developing coronary artery aneurysms who may benefit from more intensive initial treatment have been published. Advances in cardiovascular imaging have improved the ability to identify coronary artery stenosis in patients with KD, yet knowledge gaps remain regarding optimal frequency of serial imaging and the best imaging modality to identify those at risk for inducible myocardial ischemia. Recent data have advanced the understan
Source: www.ahajournals.orgCategories: General Medicine News, CardiologistsTweet-
@American_Heart @MedClubPage @AskDrShashank @DrAseemMalhotra @DrSuneelDhand @MartinKulldorff @DrJBhattacharya @MartyMakary @Hragy https://t.co/NHOaOijCt8
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Mashup Score: 10Cardio-Oncology and Heart Failure: A Scientific Statement from the Heart Failure Society of America - 11 day(s) ago
Heart failure and cancer remain two of the leading causes of morbidity and mortality and the two disease entities are linked in a complex manner. Patients with cancer are at increased risk of cardiovascular complications related to the cancer therapies. The presence of cardiomyopathy or heart failure in a patient with new cancer diagnosis portends a high risk for adverse oncology and cardiovascular outcomes. With the rapid growth of cancer therapies, many of which interfere with cardiovascular homeostasis, heart failure practitioners need to be familiar with prevention, risk stratification, diagnosis, and management strategies in cardio-oncology.
Source: onlinejcf.comCategories: General Medicine News, CardiologistsTweet-
https://t.co/XNa3kRG9a4
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Mashup Score: 6
The availability of cardiac myosin inhibitors (CMI) to treat symptomatic left ventricular outflow tract obstruction (LVOTO) and the evolving recommendation
Source: academic.oup.comCategories: General Medicine News, CardiologistsTweet-
https://t.co/BKI3Qni3cO
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Mashup Score: 4
The availability of cardiac myosin inhibitors (CMI) to treat symptomatic left ventricular outflow tract obstruction (LVOTO) and the evolving recommendation
Source: academic.oup.comCategories: General Medicine News, CardiologistsTweet-
https://t.co/BKI3Qni3cO
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Mashup Score: 2Sudden Death in Obesity: Mechanisms and Management - 17 day(s) ago
AbstractIn recent decades, the prevalence of obesity has increased significantly, leading to an epidemic at the global level. Obesity is associated with various metabolic alterations and increases …
Source: www.jacc.orgCategories: General Medicine News, CardiologistsTweet-
https://t.co/JonvTNM5C3
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Mashup Score: 0GLP-1 Receptor Agonists Among Patients With Overweight or Obesity, Diabetes, and HFpEF on SGLT2 Inhibitors: - 17 day(s) ago
AbstractBackgroundAlthough the use of glucagon-like peptide-1 receptor agonist (GLP-1 RA) in patients with obesity and heart failure with preserved ejection fraction (HFpEF) has demonstrated improv…
Source: www.jacc.orgCategories: General Medicine News, CardiologistsTweet-
https://t.co/ueIZSBGRn6
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Mashup Score: 4
The availability of cardiac myosin inhibitors (CMI) to treat symptomatic left ventricular outflow tract obstruction (LVOTO) and the evolving recommendation
Source: academic.oup.comCategories: General Medicine News, CardiologistsTweet-
https://t.co/BKI3Qni3cO
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Mashup Score: 4
The availability of cardiac myosin inhibitors (CMI) to treat symptomatic left ventricular outflow tract obstruction (LVOTO) and the evolving recommendation
Source: academic.oup.comCategories: General Medicine News, CardiologistsTweet-
https://t.co/BKI3Qni3cO
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https://t.co/wunquNIg8L