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Mashup Score: 21
Statins, ezetimibe and statins-ezetimibe combination therapy are recommended lipid-lowering therapies (LLTs) in children with heterozygous familial hypercholesterolaemia (HeFH). However, their relative effectiveness is not well understood. We aimed to compare the safety and efficacy of these therapies using direct and indirect comparisons.
Source: www.atherosclerosis-journal.comCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 30Low levels of low-density lipoprotein cholesterol, intracerebral haemorrhage, and other safety issues: is there still a matter of debate? - 1 month(s) ago
Abstract. Although some observational studies suggest a potential association of low levels of low-density lipoprotein cholesterol (LDL-C) with intracerebral ha
Source: academic.oup.comCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 50
What was known ?
Source: www.atherosclerosis-journal.comCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 29ApoB-100: The guardian of LDL stability - 2 month(s) ago
Low-density lipoprotein (LDL) particles are composed of a core containing cholesteryl esters and some triglycerides, surrounded by a monolayer of phospholipids and unesterified cholesterol. This structure is stabilized by a single apolipoprotein B-100 (apoB-100), which is anchored on the surface of the particle. This structure enables LDL particles to efficiently transport cholesterol through the bloodstream to peripheral tissues. However, once LDL particles are retained in the arterial intima, they become vulnerable to modifications—such as lipolysis—that promote particle aggregation1-3.
Source: www.atherosclerosis-journal.comCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 3Christopher Cannon, MD on LinkedIn: News details - 2 month(s) ago
New indication for GLP-1RA semaglutide: To reduce the risk of kidney disease worsening, kidney failure, and CV death in patients with type 2 diabetes and chronic kidney disease https://lnkd.in/deeH78nh
Source: www.linkedin.comCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 5Adriana Valenti Sabouret su LinkedIn: Le tracce di un patriota sardo, Matteo Luigi Simon, si perdono a… - 2 month(s) ago
Una mia nuova scoperta che condivido con gioia! #matteoluigisimon #sardarivoluzione #rivoluzionarisardiaparigi #giomariaangioy . . .
Source: it.linkedin.comCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 4Declining Trend of Sudden Cardiac Death in Younger Individuals: A 20-Year Nationwide Study | Circulation - 2 month(s) ago
BACKGROUND: Declining cardiovascular mortality rates have been well-documented, yet temporal trends of sudden cardiac death (SCD) in young individuals remain unclear. We provide contemporary nationwide estimates of the temporal trends of SCD in young individuals (1–35 years of age) from 2000 through 2019 and correlate these trends to changes in out-of-hospital cardiac arrest (OHCA) patterns, rates of inherited cardiac diseases, and implantations of implantable cardioverter defibrillators (ICD). METHODS: All individuals between 1 and 35 years of age living in Denmark from 2000 through 2019 were included, with annual re-evaluation of the at-risk population in regard to age. Adjudication of SCD cases relied on multiple sources, including death certificates, medical files, and autopsy reports. Information on OHCA, diagnostic rates, and ICD implantations were captured from nationwide administrative registries. Annual incidence rates of SCD were calculated, and temporal trends in SCD inciden
Source: www.ahajournals.orgCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 9Vascular strain of the aorta and peripheral arteries in patients with type 1 diabetes mellitus in comparison with healthy controls - 2 month(s) ago
Local variations of vascular strain may be related to the development of atherosclerotic lesions. Whether vascular strain of peripheral arteries without manifest atherosclerosis is affected by diabetes mellitus is not known. This study aimed to assess vascular strain of peripheral arteries and the abdominal aorta of young patients with type 1 diabetes mellitus (T1DM) in comparison with healthy controls.
Source: www.atherosclerosis-journal.comCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 4
Chi era e come mai fu colui che – fra i nobili fratelli –si distinse maggiormente ? Quali furono i suoi rapporti con Giovanni Maria Angioy e che tipo di vita condusse a Parigi ? A questi e altri interrogativi tenteremo di dare risposta alla luce delle nostre scoperte. Nato ad Alghero il 21 settembre 1761, fu […]
Source: www.sindipendente.comCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 6Tove Lo - "Habits (Stay High)" Live at KROQ - 2 month(s) ago
Tove Lo performs “Habits (Stay High)” in the Red Bull Sound Space at KROQ.SUBSCRIBE HERE: http://www.youtube.com/user/kroqFACEBOOK: http://www.facebook.com/w…
Source: www.youtube.comCategories: General Medicine News, CardiologistsTweet
Efficacy and safety of statins, ezetimibe and statins-ezetimibe therapies for children and adolescents with #HeFH. Article in the last issue of #Atherosclerosis #EAS journal ☀️ https://t.co/6qYdWTCJkB