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Mashup Score: 7Integrative genomic analyses identify candidate causal genes for calcific aortic valve stenosis involving tissue-specific regulation - PubMed - 1 month(s) ago
There is currently no medical therapy to prevent calcific aortic valve stenosis (CAVS). Multi-omics approaches could lead to the identification of novel molecular targets. Here, we perform a genome-wide association study (GWAS) meta-analysis including 14,819 cases among 941,863 participants of Europ …
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 73Transcatheter or Surgical Aortic Valve Replacement in Patients with Severe Aortic Stenosis and Small Aortic Annulus: A Randomized Clinical Trial - 2 month(s) ago
Background: The optimal treatment in patients with severe aortic stenosis (AS) and small aortic annulus (SAA) remains to be determined. The objectives of this study were to compare the hemodynamic an
Source: www.ahajournals.orgCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 22The Mortality Burden of Untreated Aortic Stenosis - PubMed - 3 month(s) ago
Patients with AS have high mortality risk across all levels of untreated AS severity. Aortic valve replacement rates remain low for patients with severe AS, suggesting that more research is needed to understand barriers to diagnosis and appropriate approach and timing for aortic valve replacement.
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 39“Listen to your heart” events across Canada — HVVC - 3 month(s) ago
Heart Valve Voice Canada is excited to share that the following #ListenToYourHeart stethoscope events are scheduled in support of Heart Valve Disease Awareness Day. Visit an event closest to you and “Listen To Your Heart”
Source: www.heartvalvevoice.caCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 7Deaths induced by compassionate use of hydroxychloroquine during the first COVID-19 wave: an estimate - PubMed - 4 month(s) ago
Although our estimates are limited by their imprecision, these findings illustrate the hazard of drug repurposing with low-level evidence.
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 48Comparison of Direct Oral Anticoagulants vs Vitamin K Antagonists After Transcatheter Mitral Valve Replacement: - 4 month(s) ago
Abstract Background There is currently no established recommendation for antithrombotic treatment following transcatheter mitral valve replacement (TMVR). However, based on the analogy with surgica…
Source: www.jacc.orgCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 25Cardiac Reoperation or Transcatheter Mitral Valve Replacement for Patients With Failed Mitral Prostheses: - 4 month(s) ago
Abstract Background Evidence is limited regarding patient outcomes comparing redo surgical mitral valve replacement (redo SMVR) vs transcatheter mitral valve replacement (TMVR) for failed prosthese…
Source: www.jacc.orgCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 115Sex-Specific Prognosis of Left Ventricular Size and Function Following Repair of Degenerative Mitral Regurgitation: - 4 month(s) ago
Abstract Background Prior studies have demonstrated worse long-term outcomes for women after surgery for severe mitral regurgitation (MR). The current Class I indications for surgery for severe deg…
Source: www.jacc.orgCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 22The Mortality Burden of Untreated Aortic Stenosis - PubMed - 6 month(s) ago
Patients with AS have high mortality risk across all levels of untreated AS severity. Aortic valve replacement rates remain low for patients with severe AS, suggesting that more research is needed to understand barriers to diagnosis and appropriate approach and timing for aortic valve replacement.
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 125Comprehensive Myocardial Assessment by Computed Tomography: Impact on Short-Term Outcomes After Transcatheter Aortic Valve Replacement - 6 month(s) ago
Abstract Background Quantification of myocardial changes in severe aortic stenosis (AS) is prognostically important. The potential for comprehensive myocardial assessment pre–transcatheter aortic v…
Source: www.jacc.orgCategories: General Medicine News, CardiologistsTweet
This study reports 32 genomic loci for AS, among which 20 are novel: highlight the role of lipoproteins, blood pressure and inflammation. Integrative genomic analyses identify candidate causal genes for calcific aortic valve stenosis involving tissue-sp… https://t.co/8W2BnRtlUp