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Mashup Score: 23Treatment Strategies for Advanced Classical Hodgkin Lymphoma in the Times of Dacarbazine Shortage - 7 month(s) ago
The shortage of dacarbazine (DTIC) has created an acute and unprecedented crisis in the management of patients with classical Hodgkin lymphoma, with DTIC being an essential component of doxorubicin, bleomycin, vinblastine, and DTIC (ABVD) and prior attempts at omitting DTIC from ABVD leading to substantial loss of efficacy. In this review, we discuss the strategies to manage classical Hodgkin lymphoma during the DTIC shortage and propose a treatment algorithm on the basis of fitness and ability to receive anthracyclines safely.
Source: ascopubs.orgCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 1(1) Faculty Position: Lymphoma Service | Memorial Sloan Kettering Cancer Center | LinkedIn - 11 month(s) ago
About the job At Memorial Sloan Kettering (MSK), we’re not only changing the way we treat cancer, but also the way the world thinks about it. By working together and pushing forward with innovation and discovery, we’re driving excellence and improving outcomes. We’re treating cancer, one patient at a time. Join us and make a difference every day. In compliance…
Source: www.linkedin.comCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 5Impact of monoclonal protein at diagnosis on outcomes in marginal zone lymphoma: A multicenter cohort study - 11 month(s) ago
Key Points. Patients with MZL who had M-protein at diagnosis had inferior PFS compared to those with no M-proteinMZLs producing M-protein at diagnosis have a hi
Source: American Society of HematologyCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 18
/PRNewswire/ — AbbVie (NYSE: ABBV) today announced that the U.S. Food and Drug Administration (FDA) has approved EPKINLYTM (epcoritamab-bysp), as the first…
Source: www.prnewswire.comCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 2JAANA 2023 | Jipmer Alumni Association of North America - 1 year(s) ago
19th Biennial Meeting and CME October 6 and 7, 2023 Hyatt Regency Jacksonville Riverfront Jacksonville, FL Dear fellow alumni, With COVID finally behind us and in accordance with the desire of our members, we will resume our in person biennial meetings at the Hyatt Regency Jacksonville Riverfront, FL on October 6 and 7, 2023! We have arranged for a stimulating CME…
Source: jaana.jipmer.netCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 0AMG176, an MCL-1 inhibitor, is active in pre-clinical models of aggressive B-cell lymphomas - 1 year(s) ago
Upregulation of the anti-apoptotic protein MCL-1 has been implicated in chemotherapy resistance and poor clinical outcomes in B-cell lymphoma (BCL). We report the activity of AMG176, a direct, sele…
Source: Taylor & FrancisCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 3Coronavirus (COVID-19) Update: FDA Authorizes Changes to Simplify Use of Bivalent mRNA COVID-19 Vaccines - 1 year(s) ago
The FDA amended the EUAs of the Moderna and Pfizer-BioNTech COVID-19 bivalent mRNA vaccines to simplify the vaccination schedule for most individuals.
Categories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 2Yellapragada Subbarow - Wikipedia - 1 year(s) ago
From Wikipedia, the free encyclopedia Yellapragada Subba RaoCommemorative postage stamp celebrating the birth centenary of Dr. SubbaRao (anglicized version of Subba Rao)Born12 January 1895Bhimavaram, Madras Presidency, British India(now in Andhra Pradesh, India)Died8 August 1948 (aged 53)New York City, United StatesNationalityIndianAlma materHarvard Medical SchoolMadras Medical…
Source: en.wikipedia.orgCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 0
Pevonedistat (TAK924) is a Nedd8-activating enzyme inhibitor with preclinical activity in non-Hodgkin lymphoma (NHL). This open-label, Phase I, multicenter, investigator-sponsored study enrolled patients with relapsed/refractory (R/R) NHL and chronic lymphocytic leukemia (CLL). The primary objective was safety. Pevonedistat was given intravenously on days 1, 3, 5 of a 21-day cycle for 8 cycles at…
Source: NatureCategories: Hem/Oncs, Latest HeadlinesTweet-
Nedd8 inhibition reinvigorates T-cell responses in lymphomas, in addition to NFkB inhibition. Thank you @DanilovLab for your excellent leadership on this project and our clinical trial with #pevonedistat in R/R lymphomas. https://t.co/rzx8rUEoiK #lymsm @cityofhope @RoswellPark https://t.co/e3s2MNAUPv
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Mashup Score: 1
Low-dose, daily olanzapine is a simple, inexpensive, well-tolerated intervention that significantly improves appetite and weight gain in newly diagnosed patients on chemotherapy.
Source: PubMedCategories: Hem/Oncs, Latest HeadlinesTweet
#lymsm #drugshortage With DACARBAZINE SHORTAGE knocking on our doors again, sharing this article I penned with @drrx4L @DrAEvens during the last shortage. @ASCO @JCO_ASCO. Managing Hodgkin lymphoma during dacarbazine shortage https://t.co/lSxXdV1tAu